Full Product Name
PRODH Antibody
Product Gene Name
anti-PRODH antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Other Notes
Small volumes of anti-PRODH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Testing Data of anti-PRODH antibody
NCBI/Uniprot data below describe general gene information for PRODH. It may not necessarily be applicable to this product.
NCBI Accession #
BC118597
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UniProt Secondary Accession #
O14680; Q0P507; Q147W8; Q504W1; Q59FI8; Q6NV86; Q9UF13; A6NF53[Other Products]
UniProt Related Accession #
O43272[Other Products]
Molecular Weight
59,231 Da
NCBI Official Full Name
Homo sapiens proline dehydrogenase (oxidase) 1, mRNA
NCBI Official Synonym Full Names
proline dehydrogenase 1
NCBI Official Symbol
PRODH [Similar Products]
NCBI Official Synonym Symbols
POX; PIG6; HSPOX2; PRODH1; PRODH2; TP53I6
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NCBI Protein Information
proline dehydrogenase 1, mitochondrial
UniProt Protein Name
Proline dehydrogenase 1, mitochondrial
UniProt Synonym Protein Names
Proline oxidase; Proline oxidase 2; p53-induced gene 6 protein
UniProt Gene Name
PRODH [Similar Products]
NCBI Summary for PRODH
This gene encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4). This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010]
UniProt Comments for PRODH
Converts proline to delta-1-pyrroline-5-carboxylate.
Research Articles on PRODH
1. Here, we show that Prodh-deficient mice with elevated CNS L-proline display specific deficits in high-frequency GABA-ergic transmission and gamma-band oscillations. We find that L-proline is a GABA-mimetic and can act at multiple GABA-ergic targets
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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