proline dehydrogenase (oxidase) 1, ELISA Kit

Mouse Proline dehydrogenase 1; mitochondrial (PRODH) ELISA kit; FLJ33744; HSPOX2; MGC148078; MGC148079; PIG6; POX; PRODH1; PRODH2; SCZD4; TP53I6; proline dehydrogenase 1; proline oxidase 2; proline oxidase; mitochondrial; tumor protein p53 inducible protein 6; proline dehydrogenase (oxidase) 1

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

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Small volumes of PRODH elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9329621 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the proline dehydrogenase (oxidase) 1 (PRODH) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PRODH. The ELISA analytical biochemical technique of the MBS9329621 kit is based on PRODH antibody-PRODH antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PRODH antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PRODH. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

68,036 Da

proline dehydrogenase

proline dehydrogenase 1, mitochondrial; proline oxidase; proline dehydrogenase, mitochondrial

Proline dehydrogenase 1, mitochondrial

Pro1  [Similar Products]

PROD_MOUSE

PRODH: Converts proline to delta-1-pyrroline-5-carboxylate. Defects in PRODH are the cause of hyperprolinemia type 1 (HP-1). HP-1 is a disorder characterized by elevated serum proline levels. May be involved in the psychiatric and behavioral phenotypes associated with the 22q11 velocardiofacial and DiGeorge syndrome. Defects in PRODH are associated with susceptibility to schizophrenia type 4 (SCZD4). A complex, multifactorial psychotic disorder or group of disorders characterized by disturbances in the form and content of thought (e.g. delusions, hallucinations), in mood (e.g. inappropriate affect), in sense of self and relationship to the external world (e.g. loss of ego boundaries, withdrawal), and in behavior (e.g bizarre or apparently purposeless behavior). Although it affects emotions, it is distinguished from mood disorders in which such disturbances are primary. Similarly, there may be mild impairment of cognitive function, and it is distinguished from the dementias in which disturbed cognitive function is considered primary. Some patients manifest schizophrenic as well as bipolar disorder symptoms and are often given the diagnosis of schizoaffective disorder. Belongs to the proline oxidase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Oxidoreductase; Mitochondrial; EC 1.5.5.2; Amino Acid Metabolism - arginine and proline

Cellular Component: mitochondrion; mitochondrial inner membrane

Molecular Function: amino acid binding; oxidoreductase activity; proline dehydrogenase activity

Biological Process: proline catabolic process; proline metabolic process

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