Product Name
QDPR, Blocking Peptide
Full Product Name
QDPR Peptide - C-terminal region
Product Gene Name
QDPR blocking peptide
[Similar Products]
Product Synonym Gene Name
DHPR; PKU2; SDR33C1[Similar Products]
QDPR peptide (MBS3245709) is used for blocking the activity of QDPR antibody (MBS3220912)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
Synthetic peptide located within the following region: SMPEADFSSW TPLEFLVETF HDWITGKNRP SSGSLIQVVT TEGRTELTPA
3D Structure
ModBase 3D Structure for P09417
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of QDPR blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
QDPR blocking peptide
This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.
Product Categories/Family for QDPR blocking peptide
Peptide
Applications Tested/Suitable for QDPR blocking peptide
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for QDPR. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000311.2
[Other Products]
NCBI GenBank Nucleotide #
NM_000320.2
[Other Products]
UniProt Primary Accession #
P09417
[Other Products]
UniProt Related Accession #
P09417[Other Products]
NCBI Official Full Name
dihydropteridine reductase isoform 1
NCBI Official Synonym Full Names
quinoid dihydropteridine reductase
NCBI Official Symbol
QDPR [Similar Products]
NCBI Official Synonym Symbols
DHPR; PKU2; HDHPR; SDR33C1
[Similar Products]
NCBI Protein Information
dihydropteridine reductase
UniProt Protein Name
Dihydropteridine reductase
UniProt Synonym Protein Names
HDHPR; Quinoid dihydropteridine reductase
Protein Family
Dihydropteridine reductase
UniProt Gene Name
QDPR [Similar Products]
UniProt Synonym Gene Names
DHPR [Similar Products]
UniProt Entry Name
DHPR_HUMAN
NCBI Summary for QDPR
This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase. [provided by RefSeq, Jul 2008]
Research Articles on QDPR
1. show for the first time statistically significant up regulation of iNOS in QDPR overexpressing astrocytes. Increased expression of iNOS associated with astrocyte pathology seen in many neurodegenerative disorders may have implications in autoimmune neurodegenerative disorders.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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