Full Product Name
CRX Antibody - C-terminal region
Product Gene Name
anti-CRX antibody
[Similar Products]
Product Synonym Gene Name
CRD; LCA7; OTX3; CORD2[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: SVGPSLAQSP TSLSGQSYGA YSPVDSLEFK DPTGTWKFTY NPMDPLDYKD
3D Structure
ModBase 3D Structure for O43186
Purity/Purification
Affinity purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human CRX
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-CRX antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CRX antibody
The protein encoded by this gene is a photoreceptor-specific transcription factor which plays a role in the differentiation of photoreceptor cells. This homeodomain protein is necessary for the maintenance of normal cone and rod function. Mutations in this gene are associated with photoreceptor degeneration, Leber congenital amaurosis type III and the autosomal dominant cone-rod dystrophy 2. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
Product Categories/Family for anti-CRX antibody
Polyclonal; Transcription Regulation; Disease Related;
Applications Tested/Suitable for anti-CRX antibody
Western Blot (WB)
Western Blot (WB) of anti-CRX antibody
Host: Rabbit
Target Name: CRX
Sample Tissue: Human Jurkat Whole Cell lysates
Antibody Dilution: 1ug/ml

NCBI/Uniprot data below describe general gene information for CRX. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000545.1
[Other Products]
NCBI GenBank Nucleotide #
NM_000554.5
[Other Products]
UniProt Primary Accession #
O43186
[Other Products]
UniProt Related Accession #
O43186[Other Products]
NCBI Official Full Name
cone-rod homeobox protein
NCBI Official Synonym Full Names
cone-rod homeobox
NCBI Official Symbol
CRX [Similar Products]
NCBI Official Synonym Symbols
CRD; LCA7; OTX3; CORD2
[Similar Products]
NCBI Protein Information
cone-rod homeobox protein
UniProt Protein Name
Cone-rod homeobox protein
Protein Family
Cone-rod homeobox protein
UniProt Gene Name
CRX [Similar Products]
UniProt Synonym Gene Names
CORD2 [Similar Products]
UniProt Entry Name
CRX_HUMAN
NCBI Summary for CRX
The protein encoded by this gene is a photoreceptor-specific transcription factor which plays a role in the differentiation of photoreceptor cells. This homeodomain protein is necessary for the maintenance of normal cone and rod function. Mutations in this gene are associated with photoreceptor degeneration, Leber congenital amaurosis type III and the autosomal dominant cone-rod dystrophy 2. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
Research Articles on CRX
1. that two photoreceptor-specific transcription factors, NRL and CRX, are master regulators of this program and are required for tumor maintenance in this subgroup
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
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