Product Name
(Rhesus macaque) Cytochrome c (CYCS), Recombinant Protein
Popular Item
Full Product Name
Recombinant Macaca mulatta (Rhesus macaque) Cytochrome c (CYCS)
Product Synonym Names
Recombinant (Rhesus macaque) Cytochrome c (CYCS); Cytochrome c
Product Gene Name
CYCS recombinant protein
[Similar Products]
Product Synonym Gene Name
CYCS; CYC[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
GDVEKGKKIF IMKCSQCHTV EKGGKHKTGP NLHGLFGRKT GQAPGYSYTA ANKNKGITWG EDTLMEYLEN PKKYIPGTKM IFVGIKKKEE RADLIAYLKK ATNE
Chromosome Location
Chromosome: 3; NC_007860.1 (101146136..101148668). Location: chromosome: 3
3D Structure
ModBase 3D Structure for P00002
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>=90% (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Macaca mulatta (Rhesus macaque)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of CYCS recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for CYCS. It may not necessarily be applicable to this product.
NCBI Accession #
XP_002803395.1
[Other Products]
NCBI GenBank Nucleotide #
XM_002803349.1
[Other Products]
UniProt Primary Accession #
P00002
[Other Products]
UniProt Related Accession #
P00002[Other Products]
Molecular Weight
11,737 Da[Similar Products]
NCBI Official Full Name
cytochrome c-like
NCBI Official Symbol
CYCS [Similar Products]
NCBI Protein Information
cytochrome c, somatic
UniProt Protein Name
Cytochrome c
Protein Family
Cytochrome
UniProt Gene Name
CYCS [Similar Products]
UniProt Synonym Gene Names
CYC [Similar Products]
UniProt Entry Name
CYC_MACMU
UniProt Comments for CYCS
Function: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases
By similarity.
Subcellular location: Mitochondrion intermembrane space. Note: Loosely associated with the inner membrane.
Post-translational modification: Binds 1 heme group per subunit.Phosphorylation at Tyr-49 and Tyr-98 both reduce by half the turnover in the reaction with cytochrome c oxidase, down-regulating mitochondrial respiration
By similarity.
Sequence similarities: Belongs to the cytochrome c family.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.