Product Name
40S ribosomal protein SA (RPSA), Polyclonal Antibody
Full Product Name
40S ribosomal protein SA Polyclonal Antibody
Product Synonym Names
37 kDa laminin receptor precursor; 37LRP; 37/67 kDa laminin receptor; LRP/LR; 67 kDa laminin receptor; 67LR; Colon carcinoma laminin-binding protein; Laminin receptor 1; LamR; Laminin-binding protein precursor p40; LBP/p40; Multidrug resistance-associated protein MGr1-Ag; NEM/1CHD4; RPSA; LAMBR; LAM
Product Gene Name
anti-RPSA antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P08865
Specificity
The antibody detects endogenous level of total 40S ribosomal protein SA polyclonal antibody.
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation purified
Form/Format
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Concentration
1.0 mg/ml (lot specific)
Immunogen
Recombinant Human 40S ribosomal protein SA protein
Preparation and Storage
Store at -20 degree C
Other Notes
Small volumes of anti-RPSA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-RPSA antibody
Required for the assembly and/or stability of the 40S ribosomal subunit.Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria.
Product Categories/Family for anti-RPSA antibody
Total protein Ab
Applications Tested/Suitable for anti-RPSA antibody
Western Blot (WB)
Application Notes for anti-RPSA antibody
Western Blot: 1:500 - 1:1000
Western Blot (WB) of anti-RPSA antibody
All lanes: 40S ribosomal protein SA antibody at 2ug/ml+mouse small intestine

NCBI/Uniprot data below describe general gene information for RPSA. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001291217.1
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NCBI GenBank Nucleotide #
NM_001304288.1
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UniProt Primary Accession #
P08865
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UniProt Secondary Accession #
P11085; P12030; Q16471; Q6IPD1; Q6IPD2; Q6NSD1; Q6NXQ8; Q86VC0[Other Products]
UniProt Related Accession #
P08865[Other Products]
Molecular Weight
32,854 Da[Similar Products]
NCBI Official Full Name
40S ribosomal protein SA isoform 2
NCBI Official Synonym Full Names
ribosomal protein SA
NCBI Official Symbol
RPSA [Similar Products]
NCBI Official Synonym Symbols
SA; LBP; LRP; p40; 67LR; ICAS; lamR; 37LRP; LAMBR; LAMR1; LRP/LR; LBP/p40; NEM/1CHD4
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NCBI Protein Information
40S ribosomal protein SA
UniProt Protein Name
40S ribosomal protein SA
UniProt Synonym Protein Names
37 kDa laminin receptor precursor
Protein Family
40S ribosomal protein
UniProt Gene Name
RPSA [Similar Products]
UniProt Synonym Gene Names
37LRP; LRP/LR; 67LR; LamR; LBP/p40 [Similar Products]
UniProt Entry Name
RSSA_HUMAN
UniProt Comments for RPSA
RPSA: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Belongs to the ribosomal protein S2P family.
Protein type: Ribosomal
Chromosomal Location of Human Ortholog: 3p22.2
Cellular Component: cytoplasm; cytosol; membrane; nucleoplasm; nucleus; plasma membrane
Molecular Function: protein binding; ribosome binding; structural constituent of ribosome
Biological Process: endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); mRNA catabolic process, nonsense-mediated decay; ribosomal small subunit assembly and maintenance; rRNA export from nucleus; rRNA processing; SRP-dependent cotranslational protein targeting to membrane; translation; translational initiation; viral transcription
Disease: Asplenia, Isolated Congenital
Precautions
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Disclaimer
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