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40S ribosomal protein SA, Polyclonal Antibody

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产品名称: 40S ribosomal protein SA, Polyclonal Antibody
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简单介绍

40S ribosomal protein SA, Polyclonal Antibody


40S ribosomal protein SA, Polyclonal Antibody  的详细介绍
Product Name

40S ribosomal protein SA (RPSA), Polyclonal Antibody

Full Product Name

40S ribosomal protein SA Polyclonal Antibody

Product Synonym Names
37 kDa laminin receptor precursor; 37LRP; 37/67 kDa laminin receptor; LRP/LR; 67 kDa laminin receptor; 67LR; Colon carcinoma laminin-binding protein; Laminin receptor 1; LamR; Laminin-binding protein precursor p40; LBP/p40; Multidrug resistance-associated protein MGr1-Ag; NEM/1CHD4; RPSA; LAMBR; LAM
Product Gene Name

anti-RPSA antibody

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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OMIM
150370
3D Structure
ModBase 3D Structure for P08865
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Specificity
The antibody detects endogenous level of total 40S ribosomal protein SA polyclonal antibody.
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation purified
Form/Format
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Concentration
1.0 mg/ml (lot specific)
Immunogen
Recombinant Human 40S ribosomal protein SA protein
Immunogen Type
Protein
Preparation and Storage
Store at -20 degree C
Other Notes
Small volumes of anti-RPSA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
anti-RPSA antibody
Required for the assembly and/or stability of the 40S ribosomal subunit.Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria.
Product Categories/Family for anti-RPSA antibody
Total protein Ab
Applications Tested/Suitable for anti-RPSA antibody
Western Blot (WB)
Application Notes for anti-RPSA antibody
Western Blot: 1:500 - 1:1000

Western Blot (WB) of anti-RPSA antibody
All lanes: 40S ribosomal protein SA antibody at 2ug/ml+mouse small intestine
anti-RPSA antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for RPSA. It may not necessarily be applicable to this product.
NCBI GI #
747165389
NCBI GeneID
3921
NCBI Accession #
NP_001291217.1 [Other Products]
NCBI GenBank Nucleotide #
NM_001304288.1 [Other Products]
UniProt Primary Accession #
P08865 [Other Products]
UniProt Secondary Accession #
P11085; P12030; Q16471; Q6IPD1; Q6IPD2; Q6NSD1; Q6NXQ8; Q86VC0[Other Products]
UniProt Related Accession #
P08865[Other Products]
Molecular Weight
32,854 Da[Similar Products]
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NCBI Official Full Name
40S ribosomal protein SA isoform 2
NCBI Official Synonym Full Names
ribosomal protein SA
NCBI Official Symbol
RPSA  [Similar Products]
NCBI Official Synonym Symbols
SA; LBP; LRP; p40; 67LR; ICAS; lamR; 37LRP; LAMBR; LAMR1; LRP/LR; LBP/p40; NEM/1CHD4
  [Similar Products]
NCBI Protein Information
40S ribosomal protein SA
UniProt Protein Name
40S ribosomal protein SA
UniProt Synonym Protein Names
37 kDa laminin receptor precursor
Protein Family
40S ribosomal protein
UniProt Gene Name
RPSA  [Similar Products]
UniProt Synonym Gene Names
37LRP; LRP/LR; 67LR; LamR; LBP/p40  [Similar Products]
UniProt Entry Name
RSSA_HUMAN
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UniProt Comments for RPSA
RPSA: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Belongs to the ribosomal protein S2P family.

Protein type: Ribosomal

Chromosomal Location of Human Ortholog: 3p22.2

Cellular Component: cytoplasm; cytosol; membrane; nucleoplasm; nucleus; plasma membrane

Molecular Function: protein binding; ribosome binding; structural constituent of ribosome

Biological Process: endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); mRNA catabolic process, nonsense-mediated decay; ribosomal small subunit assembly and maintenance; rRNA export from nucleus; rRNA processing; SRP-dependent cotranslational protein targeting to membrane; translation; translational initiation; viral transcription

Disease: Asplenia, Isolated Congenital
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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