Product Name
SLC26A1, cDNA Clone
Full Product Name
SLC26A1 cDNA Clone
Product Gene Name
SLC26A1 cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggacgagt cccctgagcc tctgcagcag ggcagagggc cggtgccggt ccgacggcag cgcccagcac cccggggtct gcgtgagatg ctgaaggcca ggctgtggtg cagctgctcg tgcagtgtgc tgtgcgtccg ggcgctggtg caggacctgc tccccgccac gcgctggctg cgtcagtacc gcccgcggga gtacctggca ggcgacgtca tgtctgggct ggtcatcggc atcatcctgg tgccgcaggc catcgcctac tcattgctgg ccgggctgca gcccatctac agcctctata cgtccttctt cgccaacctc atctacttcc tcatgggcac ctcacggcat gtctccgtgg gcatcttcag cctgctttgc ctcatggtgg ggcaggtggt ggaccgggag ctccagctgg ccggctttga cccctcccag gacggcctgc agcccggagc caacagcagc accctcaacg gctcggctgc catgctggac tgcgggcgtg actgctacgc catccgtgtc gccaccgccc tcacgctgat gaccgggctt taccagacgt cctggggtag aaacagcttc cagcaacacc catggcaatt aacacagagg agtgactcgc aggaacttct ggaagaggag gaaagatctt gctga
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of SLC26A1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for SLC26A1. It may not necessarily be applicable to this product.
NCBI Accession #
BC015517
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UniProt Secondary Accession #
Q7Z5R3; Q96BK0; A8K9N2[Other Products]
UniProt Related Accession #
Q9H2B4[Other Products]
Molecular Weight
24,962 Da
NCBI Official Full Name
Homo sapiens solute carrier family 26 (sulfate transporter), member 1, mRNA
NCBI Official Synonym Full Names
solute carrier family 26 member 1
NCBI Official Symbol
SLC26A1 [Similar Products]
NCBI Official Synonym Symbols
CAON; EDM4; SAT1; SAT-1
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NCBI Protein Information
sulfate anion transporter 1
UniProt Protein Name
Sulfate anion transporter 1
UniProt Synonym Protein Names
Solute carrier family 26 member 1
Protein Family
Sulfate anion transporter
UniProt Gene Name
SLC26A1 [Similar Products]
UniProt Synonym Gene Names
SAT1; SAT-1 [Similar Products]
UniProt Entry Name
S26A1_HUMAN
NCBI Summary for SLC26A1
This gene is a member of a family of sulfate/anion transporter genes. Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures, but have markedly different tissue expression patterns. This gene is primarily expressed in the liver, pancreas, and brain. Three splice variants that encode different isoforms have been identified. [provided by RefSeq, Jul 2008]
UniProt Comments for SLC26A1
SLC26A1: High affinity uptake of sulfate. Accepts oxalate, but not succinate as a cosubstrate. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transporter, SLC family; Membrane protein, multi-pass; Transporter; Membrane protein, integral
Chromosomal Location of Human Ortholog: 4p16.3
Cellular Component: integral to membrane; integral to plasma membrane; plasma membrane
Molecular Function: anion:anion antiporter activity; bicarbonate transmembrane transporter activity; chloride channel activity; chloride transmembrane transporter activity; oxalate transmembrane transporter activity; sulfate transmembrane transporter activity
Biological Process: 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process; bicarbonate transport; chloride transport; ion transport; oxalate transport; regulation of intracellular pH; regulation of membrane potential; sulfate transport
Disease: Nephrolithiasis, Calcium Oxalate
Research Articles on SLC26A1
1. Screened the SLC26A1 gene in a cohort of 13 individuals with recurrent calcium oxalate urolithiasis, which is the commonest type. DNA sequence analyses showed missense mutations in seven patients.
Precautions
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Disclaimer
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