Product Name
SLC26A1, Blocking Peptide
Full Product Name
SLC26A1 Peptide - middle region
Product Gene Name
SLC26A1 blocking peptide
[Similar Products]
Product Synonym Gene Name
EDM4; SAT-1; SAT1[Similar Products]
SLC26A1 peptide (MBS3232135) is used for blocking the activity of SLC26A1 antibody (MBS3207170)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
ACCSPPVRDI LSRGGFLGEG PGDTAEEEQL FLSVHDAVQT ARARHRELEA
3D Structure
ModBase 3D Structure for Q9H2B4
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of SLC26A1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
SLC26A1 blocking peptide
This is a synthetic peptide designed for use in combination with anti-SLC26A1 Antibody, made
Target Description: SLC26A1 is a member of sulfate/anion transporter family. Family members are well conserved in their protein (aa length among species) structures, but have markedly different tissue expression patterns. Its gene is primarily expressed in the liver, pancreas, and brain.
Product Categories/Family for SLC26A1 blocking peptide
Peptide
Applications Tested/Suitable for SLC26A1 blocking peptide
Immunohistochemistry (IHC), Western Blot (WB)
NCBI/Uniprot data below describe general gene information for SLC26A1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_071325
[Other Products]
NCBI GenBank Nucleotide #
NM_022042
[Other Products]
UniProt Primary Accession #
Q9H2B4
[Other Products]
UniProt Related Accession #
Q9H2B4[Other Products]
NCBI Official Full Name
sulfate anion transporter 1 isoform a
NCBI Official Synonym Full Names
solute carrier family 26 member 1
NCBI Official Symbol
SLC26A1 [Similar Products]
NCBI Official Synonym Symbols
CAON; EDM4; SAT1; SAT-1
[Similar Products]
NCBI Protein Information
sulfate anion transporter 1
UniProt Protein Name
Sulfate anion transporter 1
UniProt Synonym Protein Names
Solute carrier family 26 member 1
Protein Family
Sulfate anion transporter
UniProt Gene Name
SLC26A1 [Similar Products]
UniProt Synonym Gene Names
SAT1; SAT-1 [Similar Products]
UniProt Entry Name
S26A1_HUMAN
NCBI Summary for SLC26A1
This gene is a member of a family of sulfate/anion transporter genes. Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures, but have markedly different tissue expression patterns. This gene is primarily expressed in the liver, pancreas, and brain. Three splice variants that encode different isoforms have been identified. [provided by RefSeq, Jul 2008]
UniProt Comments for SLC26A1
SLC26A1: High affinity uptake of sulfate. Accepts oxalate, but not succinate as a cosubstrate. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral; Transporter
Chromosomal Location of Human Ortholog: 4p16.3
Cellular Component: integral to membrane; integral to plasma membrane; plasma membrane
Molecular Function: anion:anion antiporter activity; bicarbonate transmembrane transporter activity; chloride channel activity; chloride transmembrane transporter activity; oxalate transmembrane transporter activity; secondary active sulfate transmembrane transporter activity; sulfate transmembrane transporter activity
Biological Process: 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process; 3'-phosphoadenosine 5'-phosphosulfate metabolic process; bicarbonate transport; carbohydrate metabolic process; chloride transport; glycosaminoglycan metabolic process; ion transport; oxalate transport; regulation of intracellular pH; regulation of membrane potential; sulfate transport; transmembrane transport; xenobiotic metabolic process
Research Articles on SLC26A1
1. SLC26A1 L348P was associated with lower whole-body bone mineral density (BMD) and higher serum calcium, consistent with the osteochondrodysplasia exhibited by dogs and sheep with naturally occurring, homozygous, loss-of-function mutations in Slc13a1
Precautions
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Disclaimer
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