GH/Growth hormone, Recombinant Protein

GH; GH1; Somatotropin; Growth hormone; GH; GH-N; Growth hormone 1; Pituitary growth hormone

For Research Use Only. Not for use in diagnostic procedures.

E Coli

> 95% by SDS-PAGE.

Lyophilized from a 0.2 muM filtered solution of PBS, pH 7.4.

Store the lyophilized protein at-20 degree C to-80 degree C for long term.
After reconstitution, the protein solution is stable at-20 degree C for 3 months, at 2-8 degree C for up to 1 week.

Small volumes of GH recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Description: Recombinant Human GH/Growth hormone Protein is produced by e coli expression system. The target protein is expressed with sequence (Phe27-Phe217) of human GH/Growth hormone (Accession #P01241).
Background: Growth hormone (GH), also known as somatotropin, is a member of a family of growth factors. It plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and othertissues to secrete IGF-1. GH includes prolactin, placental lactogens, proliferins, and somatolactin. It issynthesized primarily by somatotropes in the anterior pituitary and is stored in secretory granules. It stimulatesboth the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and proteinsynthesis in muscle and other tissues.

Recombinant Human CD32/Fc-gamma RII-b Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.

22,992 Da

growth hormone 1

somatotropin

Somatotropin

GH; GH-N  [Similar Products]

The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. [provided by RefSeq, Jul 2008]

Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.

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