Full Product Name
TRPA1 Polyclonal Antibody
Product Synonym Names
Transient receptor potential cation channel subfamily A member 1; Ankyrin-like with transmembrane domains protein 1; Transformation-sensitive protein p120; TRPA1; ANKTM1
Product Gene Name
anti-TRPA1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for O75762
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-TRPA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-TRPA1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-TRPA1 antibody
WB: 1:500-2000
ELISA: 1:5000-20000
NCBI/Uniprot data below describe general gene information for TRPA1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_015628.2
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NCBI GenBank Nucleotide #
NM_007332.2
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UniProt Primary Accession #
O75762
[Other Products]
UniProt Secondary Accession #
A6NIN6[Other Products]
UniProt Related Accession #
O75762[Other Products]
NCBI Official Full Name
transient receptor potential cation channel subfamily A member 1
NCBI Official Synonym Full Names
transient receptor potential cation channel subfamily A member 1
NCBI Official Symbol
TRPA1 [Similar Products]
NCBI Official Synonym Symbols
FEPS; FEPS1; ANKTM1
[Similar Products]
NCBI Protein Information
transient receptor potential cation channel subfamily A member 1
UniProt Protein Name
Transient receptor potential cation channel subfamily A member 1
UniProt Synonym Protein Names
Ankyrin-like with transmembrane domains protein 1; Transformation-sensitive protein p120
Protein Family
Transient receptor potential cation channel subfamily
UniProt Gene Name
TRPA1 [Similar Products]
UniProt Synonym Gene Names
ANKTM1 [Similar Products]
NCBI Summary for TRPA1
The structure of the protein encoded by this gene is highly related to both the protein ankyrin and transmembrane proteins. The specific function of this protein has not yet been determined; however, studies indicate the function may involve a role in signal transduction and growth control. [provided by RefSeq, Jul 2008]
UniProt Comments for TRPA1
Receptor-activated non-selective cation channel involved in detection of pain and possibly also in cold perception and inner ear function (PubMed:25389312, PubMed:25855297). Has a central role in the pain response to endogenous inflammatory mediators and to a diverse array of volatile irritants, such as mustard oil, cinnamaldehyde, garlic and acrolein, an irritant from tears gas and vehicule exhaust fumes (PubMed:25389312, PubMed:20547126). Is also activated by menthol (in vitro)(PubMed:25389312). Acts also as a ionotropic cannabinoid receptor by being activated by delta9-tetrahydrocannabinol (THC), the psychoactive component of marijuana (PubMed:25389312). May be a component for the mechanosensitive transduction channel of hair cells in inner ear, thereby participating in the perception of sounds. Probably operated by a phosphatidylinositol second messenger system ().
Research Articles on TRPA1
1. data suggest that the most strictly conserved N-terminal ARs define the energetics of the TRPA1 channel gate and contribute to chemical-, calcium- and voltage-dependence.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
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