Product Name
Acyl-coenzyme A thioesterase 12 (Acot12), Recombinant Protein
Full Product Name
Recombinant Rat Acyl-coenzyme A thioesterase 12 (Acot12)
Product Gene Name
Acot12 recombinant protein
[Similar Products]
Product Synonym Gene Name
Acot12[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-556aa, full length protein
Sequence
MEPTVAPGEV LMSQAIQPAH ADSRGELSAG QLLKWMDTTA CLAAEKHAGI SCVTASMDDI LFEDTARIGQ IVTIRAKVTR AFSTSMEISI KVRVQDKFTG IQKLLCVAFS TFVVKPLGKE KVHLKPVLLQ TEQEQVEHRL ASERRKVRLQ HENTFSNIMK ESNWLRDPVC NEEEGTATTM ATSVQSIELV LPPHANHHGN TFGGQIMAWM ETVATISASR LCHGHPFLKS VDMFKFRGPS TVGDRLVFNA IVNNTFQNSV EVGVRVEAFD CREWAEGQGR HINSAFLIYN AVDDQEELIT FPRIQPISKD DFRRYQGAIA RRRIRLGRKY VISHKKEVPL GTQWDISKKG SISNTNVEAL KNLASKSGWE ITTTLEKIKI YTLEEQDAIS VKVEKQVGSP ARVAYHLLSD FTKRPLWDPH YISCEVIDQV SEDDQIYYIT CSVVNGDKPK DFVVLVSQRK PLKDDNTYIV ALMSVVLPSV PPSPQYIRSQ VICAGFLIQP VDSSSCTVAY LNQMSDSILP YFAGNIGGWS KSIEEAAASC IKFIENATHD GLKSVL
3D Structure
ModBase 3D Structure for Q99NB7
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Acot12 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Acot12. It may not necessarily be applicable to this product.
NCBI Accession #
NP_570103.1
[Other Products]
NCBI GenBank Nucleotide #
NM_130747.1
[Other Products]
UniProt Primary Accession #
Q99NB7
[Other Products]
UniProt Related Accession #
Q99NB7[Other Products]
Molecular Weight
62,018 Da
NCBI Official Full Name
acyl-coenzyme A thioesterase 12
NCBI Official Synonym Full Names
acyl-CoA thioesterase 12
NCBI Official Symbol
Acot12 [Similar Products]
NCBI Official Synonym Symbols
Cach; rACH
[Similar Products]
NCBI Protein Information
acyl-coenzyme A thioesterase 12
UniProt Protein Name
Acyl-coenzyme A thioesterase 12
UniProt Synonym Protein Names
Acyl-CoA thioester hydrolase 12; Cytoplasmic acetyl-CoA hydrolase 1; CACH-1; rACH; rCACH-1
Protein Family
Acyl-coenzyme A thioesterase
UniProt Gene Name
Acot12 [Similar Products]
UniProt Synonym Gene Names
Cach; Cach1; Acyl-CoA thioesterase 12; CACH-1; rACH; rCACH-1 [Similar Products]
NCBI Summary for Acot12
acetyl-CoA hydrolase found in cytoplasm [RGD, Feb 2006]
UniProt Comments for Acot12
Hydrolyzes acetyl-CoA to acetate and CoA.
Research Articles on Acot12
1. The results suggest that cytosolic acetyl-CoA levels in the liver are controlled by lipid metabolites and hormones, which result in allosteric enzymatic and transcriptional regulation of ACOT12.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
