Product Name
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial (Clpx), Recombinant Protein
Full Product Name
Recombinant Rat ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial (Clpx)
Product Gene Name
Clpx recombinant protein
[Similar Products]
Product Synonym Gene Name
Clpx[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
57-633aa, Full Length of Mature Protein
Sequence
FSETPAYFAS KDGTNKDGSG DGNKKSVTEG SSKKSGSGNS GKGGNQLRCP KCGDLCTHVE TFVSSTRFVK CEKCHHFFVV LSEADSKKSI IKEPESAAEA VKLAFQQKPP PPPKKIYNYL DKYVVGQSFA KKVLSVAVYN HYKRIYNNIP ANLRQQAEVE KQTSLTPREL EIRRREDEYR FTKLLQIAGI SPHGNALGAS MQQQGSQQMP QEKRGGEVLD SPHDDIKLEK SNILLLGPTG SGKTLLAQTL AKCLDVPFAI CDCTTLTQAG YVGEDIESVI AKLLQDANYN VEKAQQGIVF LDEVDKIGSV PGIHQLRDVG GEGVQQGLLK LLEGTIVNVP EKNSRKLRGE TVQVDTTNIL FVASGAFNGL DRIISRRKNE KYLGFGTPSN LGKGRRAAAA ADLANRSGES NTHQDIEEKD RLLRHVEARD LIEFGMIPEF VGRLPVVVPL HSLDEKTLVQ ILTEPRNAVI PQYQALFSMD KCELNVTEDA LKAIARLALE RKTGARGLRS IMEKLLLEPM FEVPNSDIVC VEVDKEVVEG KKEPGYIRAP SKESSEEDYD SGVEEDGWPR QADAANS
3D Structure
ModBase 3D Structure for Q5U2U0
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Clpx recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Clpx. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001007804.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001007803.1
[Other Products]
UniProt Primary Accession #
Q5U2U0
[Other Products]
UniProt Related Accession #
Q5U2U0[Other Products]
Molecular Weight
69,208 Da
NCBI Official Full Name
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial
NCBI Official Synonym Full Names
caseinolytic mitochondrial matrix peptidase chaperone subunit
NCBI Official Symbol
Clpx [Similar Products]
NCBI Protein Information
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial
UniProt Protein Name
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial
Protein Family
ATP-dependent Clp protease ATP-binding
UniProt Gene Name
Clpx [Similar Products]
UniProt Comments for Clpx
ATP-dependent specificity component of the Clp protease complex. Hydrolyzes ATP. Targets specific substrates for degradation by the Clp complex. Can perform chaperone functions in the absence of CLPP. Enhances the DNA-binding activity of TFAM and is required for maintaining a normal mitochondrial nucleoid structure. ATP-dependent unfoldase that stimulates the incorporation of the pyridoxal phosphate cofactor into 5-aminolevulinate synthase, thereby activating 5-aminolevulinate (ALA) synthesis, the first step in heme biosynthesis. Important for efficient erythropoiesis through upregulation of heme biosynthesis.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
