Full Product Name
BBS9 Antibody
Product Synonym Names
B1; D1; C18; PTHB1
Product Gene Name
anti-BBS9 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q3SYG4
Specificity
The antibody detects endogenous levels of total BBS9 protein.
Purity/Purification
Antigen Affinity Purification
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
0.8 mg/ml (lot specific)
Immunogen
Fusion protein of human BBS9
Preparation and Storage
Store at -20 degree C
Other Notes
Small volumes of anti-BBS9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-BBS9 antibody
This gene is downregulated by parathyroid hormone in osteoblastic cells, and therefore, is thought to be involved in parathyroid hormone action in bones. The exact function of this gene has not yet been determined. Alternatively spliced transcript variants encoding different isoformshave been identified.
Product Categories/Family for anti-BBS9 antibody
Total protein Ab
Applications Tested/Suitable for anti-BBS9 antibody
Immunohistochemistry (IHC)
Application Notes for anti-BBS9 antibody
Immunohistochemistry: 1:25-1:100
Immunohistochemistry (IHC) of anti-BBS9 antibody
Immunohistochemical analysis of paraffin-embedded Human brain tissue using at dilution 1/20,
NCBI/Uniprot data below describe general gene information for BBS9. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001028776.1
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NCBI GenBank Nucleotide #
NM_001033604.1
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UniProt Primary Accession #
Q3SYG4
[Other Products]
UniProt Secondary Accession #
P78514; Q7KYS6; Q7KYS7; Q8N570; Q99844; Q99854; Q9Y699; Q9Y6A0; E9PDC9[Other Products]
UniProt Related Accession #
Q3SYG4[Other Products]
Molecular Weight
98,683 Da
NCBI Official Full Name
protein PTHB1 isoform 3
NCBI Official Synonym Full Names
Bardet-Biedl syndrome 9
NCBI Official Symbol
BBS9 [Similar Products]
NCBI Official Synonym Symbols
B1; D1; C18; PTHB1
[Similar Products]
NCBI Protein Information
protein PTHB1
UniProt Protein Name
Protein PTHB1
UniProt Synonym Protein Names
Bardet-Biedl syndrome 9 protein; Parathyroid hormone-responsive B1 gene protein
UniProt Gene Name
BBS9 [Similar Products]
UniProt Synonym Gene Names
PTHB1 [Similar Products]
UniProt Entry Name
PTHB1_HUMAN
UniProt Comments for BBS9
The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. Required for proper BBSome complex assembly and its ciliary localization.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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