Full Product Name
ADH1B Rabbit Polyclonal
Product Gene Name
anti-ADH1B antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse, Rat
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Immunogen
Alcohol dehydrogenase 1B (class I), beta polypeptide
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-ADH1B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ADH1B antibody
ELISA (EIA), Western Blot (WB)
NCBI/Uniprot data below describe general gene information for ADH1B. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000659.2
[Other Products]
NCBI GenBank Nucleotide #
NM_000668.5
[Other Products]
UniProt Secondary Accession #
Q13711; Q4ZGI9; Q96KI7; A8MYN5; B4DRS9; B4DVC3[Other Products]
UniProt Related Accession #
P00325[Other Products]
Molecular Weight
35,412 Da
NCBI Official Full Name
alcohol dehydrogenase 1B isoform 1
NCBI Official Synonym Full Names
alcohol dehydrogenase 1B (class I), beta polypeptide
NCBI Official Symbol
ADH1B [Similar Products]
NCBI Official Synonym Symbols
ADH2; HEL-S-117
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NCBI Protein Information
alcohol dehydrogenase 1B
UniProt Protein Name
Alcohol dehydrogenase 1B
UniProt Synonym Protein Names
Alcohol dehydrogenase subunit beta
UniProt Gene Name
ADH1B [Similar Products]
UniProt Synonym Gene Names
ADH2 [Similar Products]
UniProt Entry Name
ADH1B_HUMAN
NCBI Summary for ADH1B
The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
UniProt Comments for ADH1B
ADH1B: Dimer of identical or non-identical chains of three types; alpha, beta and gamma. Belongs to the zinc-containing alcohol dehydrogenase family.
Protein type: Amino Acid Metabolism - tyrosine; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Cofactor and Vitamin Metabolism - retinol; EC 1.1.1.1; Lipid Metabolism - fatty acid; Oxidoreductase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - metabolism by cytochrome P450
Chromosomal Location of Human Ortholog: 4q23
Cellular Component: cytosol
Molecular Function: alcohol dehydrogenase activity, zinc-dependent; zinc ion binding
Biological Process: ethanol oxidation
Disease: Alcohol Dependence
Research Articles on ADH1B
1. The presence of the ADH1B*2 allele and the active ALDH2*1/*1 genotype increased the odds ratio for a high TG level.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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