Product Name
SLC25A20, Polyclonal Antibody
Full Product Name
SLC25A20 antibody - middle region
Product Gene Name
anti-SLC25A20 antibody
[Similar Products]
Product Synonym Gene Name
CAC; CACT[Similar Products]
Antibody/Peptide Pairs
SLC25A20 peptide (MBS3231976) is used for blocking the activity of SLC25A20 antibody (MBS3207010)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: SSGESKYTGT LDCAKKLYQE FGIRGIYKGT VLTLMRDVPA SGMYFMTYEW
3D Structure
ModBase 3D Structure for O43772
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 79%; Dog: 93%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%; Sheep: 86%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human SLC25A20
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-SLC25A20 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SLC25A20 antibody
This is a rabbit polyclonal antibody against SLC25A20. It was validated on Western Blot using a cell lysate as a positive control.
Target Description: SLC25A20 is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space.It mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by
Product Categories/Family for anti-SLC25A20 antibody
Polyclonal; Membrane Protein; Drugs and Drug Metabolism;
Applications Tested/Suitable for anti-SLC25A20 antibody
Western Blot (WB)
Western Blot (WB) of anti-SLC25A20 antibody
WB Suggested Anti-SLC25A20 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: HT1080 cell lysateSLC25A20 is supported by BioGPS gene expression data to be expressed in HT1080
NCBI/Uniprot data below describe general gene information for SLC25A20. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000378
[Other Products]
NCBI GenBank Nucleotide #
NM_000387
[Other Products]
UniProt Primary Accession #
O43772
[Other Products]
UniProt Related Accession #
O43772[Other Products]
NCBI Official Full Name
mitochondrial carnitine/acylcarnitine carrier protein
NCBI Official Synonym Full Names
solute carrier family 25 member 20
NCBI Official Symbol
SLC25A20 [Similar Products]
NCBI Official Synonym Symbols
CAC; CACT
[Similar Products]
NCBI Protein Information
mitochondrial carnitine/acylcarnitine carrier protein
UniProt Protein Name
Mitochondrial carnitine/acylcarnitine carrier protein
UniProt Synonym Protein Names
Carnitine/acylcarnitine translocase; CAC; Solute carrier family 25 member 20
Protein Family
Mitochondrial carnitine/acylcarnitine carrier protein
UniProt Gene Name
SLC25A20 [Similar Products]
UniProt Synonym Gene Names
CAC; CACT; CAC [Similar Products]
UniProt Entry Name
MCAT_HUMAN
NCBI Summary for SLC25A20
This gene product is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants. [provided by RefSeq, Jul 2008]
UniProt Comments for SLC25A20
Function: Mediates the transport of acylcarnitines of different length across the mitochondrial inner membrane from the cytosol to the mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway.
Research Articles on SLC25A20
1. G, we have identified a novel c.1A>G mutation. Patients with Carnitine-acylcarnitine translocase deficiency with a genotype of c.199-10T>G mutation usually presents with a severe clinical phenotype. Early recognition and appropriate treatment is crucial in this highly lethal disorder.">we report the first 2 cases of CACTD identified from the mainland China. Apart from a founder mutation c.199-10T>G, we have identified a novel c.1A>G mutation. Patients with Carnitine-acylcarnitine translocase deficiency with a genotype of c.199-10T>G mutation usually presents with a severe clinical phenotype. Early recognition and appropriate treatment is crucial in this highly lethal disorder.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
