Product Synonym Names
CLRP; CSNB1; CSNB1A; CSNB4; NBM1
Product Gene Name
anti-NYX antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9GZU5
Species Reactivity
Human, Mouse
Purity/Purification
Affinity purification
Immunogen
Recombinant protein of human NYX
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Aliquot and store at-20 degree C. Avoid repeated freeze/thaw cycles.
Other Notes
Small volumes of anti-NYX antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-NYX antibody
The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB.
Applications Tested/Suitable for anti-NYX antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-NYX antibody
WB: 1:500-1:2000
IHC: 1:50-1:100
NCBI/Uniprot data below describe general gene information for NYX. It may not necessarily be applicable to this product.
NCBI Accession #
NP_072089.1
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NCBI GenBank Nucleotide #
NM_022567.2
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UniProt Primary Accession #
Q9GZU5
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UniProt Secondary Accession #
Q2M1S4; Q5H983; Q9H4J0; D3DWC0[Other Products]
UniProt Related Accession #
Q9GZU5[Other Products]
NCBI Official Full Name
nyctalopin
NCBI Official Synonym Full Names
nyctalopin
NCBI Official Symbol
NYX [Similar Products]
NCBI Official Synonym Symbols
CLRP; NBM1; CSNB1; CSNB4; CSNB1A
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NCBI Protein Information
nyctalopin
UniProt Protein Name
Nyctalopin
Protein Family
Nyctalopin
UniProt Gene Name
NYX [Similar Products]
UniProt Synonym Gene Names
CLRP [Similar Products]
NCBI Summary for NYX
The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB. [provided by RefSeq, Oct 2008]
Research Articles on NYX
1. Two Novel NYX Gene Mutations in the Chinese Families with X-linked Congenital Stationary Night Blindness were described.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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