Product Name
3-ketoacyl-CoA thiolase (ACAA1), Polyclonal Antibody
Full Product Name
Rabbit anti-human 3-ketoacyl-CoA thiolase, peroxisomal polyclonal Antibody(ACAA1)
Product Synonym Names
Acetyl-CoA acyltransferase; Beta-ketothiolase; Peroxisomal 3-oxoacyl-CoA thiolase; ACAA1; ACAA; PTHIO
Product Gene Name
anti-ACAA1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P09110
Purity/Purification
Antigen Affinity Purified
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Immunogen
Recombinant human 3-ketoacyl-CoA thiolase, peroxisomal protein (27-300aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-99258
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-ACAA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ACAA1 antibody
This gene encodes an enzyme operative in the beta-oxidation system of the peroxisomes. Deficiency of this enzyme leads to pseudo-Zellweger syndrome. Alternative splicing results in multiple transcript variants.
Applications Tested/Suitable for anti-ACAA1 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-ACAA1 antibody
Recommended dilution: IHC:1:20-1:200
Immunohistochemistry (IHC) of anti-ACAA1 antibody
Immunohistochemistry of paraffin-embedded human liver cancer using MBS1492126 at dilution 1:100
NCBI/Uniprot data below describe general gene information for ACAA1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001123882.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001130410.1
[Other Products]
UniProt Primary Accession #
P09110
[Other Products]
UniProt Secondary Accession #
Q96CA6; G5E935[Other Products]
UniProt Related Accession #
P09110[Other Products]
Molecular Weight
34,665 Da
NCBI Official Full Name
3-ketoacyl-CoA thiolase, peroxisomal isoform b
NCBI Official Synonym Full Names
acetyl-CoA acyltransferase 1
NCBI Official Symbol
ACAA1 [Similar Products]
NCBI Official Synonym Symbols
ACAA; THIO; PTHIO
[Similar Products]
NCBI Protein Information
3-ketoacyl-CoA thiolase, peroxisomal
UniProt Protein Name
3-ketoacyl-CoA thiolase, peroxisomal
UniProt Synonym Protein Names
Acetyl-CoA acyltransferase; Beta-ketothiolase; Peroxisomal 3-oxoacyl-CoA thiolase
Protein Family
3-ketoacyl-CoA thiolase
UniProt Gene Name
ACAA1 [Similar Products]
UniProt Synonym Gene Names
ACAA; PTHIO [Similar Products]
UniProt Entry Name
THIK_HUMAN
NCBI Summary for ACAA1
This gene encodes an enzyme operative in the beta-oxidation system of the peroxisomes. Deficiency of this enzyme leads to pseudo-Zellweger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
UniProt Comments for ACAA1
ACAA1: an enzyme operative in the beta-oxidation system of the peroxisomes. Deficiency of this enzyme leads to pseudo-Zellweger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Protein type: Lipid Metabolism - fatty acid; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Lipid Metabolism - unsaturated fatty acid biosynthesis; Acetyltransferase; EC 2.3.1.16
Chromosomal Location of Human Ortholog: 3p22.2
Cellular Component: intracellular membrane-bound organelle; membrane; peroxisomal matrix; peroxisome
Molecular Function: acetyl-CoA C-acyltransferase activity; palmitoyl-CoA oxidase activity; protein binding
Biological Process: bile acid metabolic process; cellular lipid metabolic process; fatty acid beta-oxidation; fatty acid beta-oxidation using acyl-CoA oxidase; unsaturated fatty acid metabolic process; very-long-chain fatty acid metabolic process
Disease: D-bifunctional Protein Deficiency
Research Articles on ACAA1
1. Findings suggest that protective effects of endotoxin exposure on asthma may vary depending upon the presence or absence of a polymorphism in ACAA1.
Precautions
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Disclaimer
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