Full Product Name
EMD antibody - N-terminal region
Product Gene Name
anti-EMD antibody
[Similar Products]
Product Synonym Gene Name
EDMD; LEMD5; STA[Similar Products]
Antibody/Peptide Pairs
EMD peptide (MBS3240777) is used for blocking the activity of EMD antibody (MBS3215875)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: YEKKIFEYET QRRRLSPPSS SAASSYSFSD LNSTRGDADM YDLPKKEDAL
3D Structure
ModBase 3D Structure for P50402
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 92%; Dog: 92%; Guinea Pig: 100%; Horse: 92%; Human: 100%; Mouse: 92%; Rabbit: 83%; Rat: 100%
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-EMD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-EMD antibody
This is a rabbit polyclonal antibody against EMD. It was validated on Western Blot
Target Description: Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene.
Product Categories/Family for anti-EMD antibody
Polyclonal; Membrane & Traffic;
Applications Tested/Suitable for anti-EMD antibody
Western Blot (WB)
Western Blot (WB) of anti-EMD antibody
WB Suggested Anti-EMD Antibody
Titration: 1.0 ug/ml
Positive Control: MCF7 Whole CellEMD is supported by BioGPS gene expression data to be expressed in MCF7
NCBI/Uniprot data below describe general gene information for EMD. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000108
[Other Products]
NCBI GenBank Nucleotide #
NM_000117
[Other Products]
UniProt Primary Accession #
P50402
[Other Products]
UniProt Related Accession #
P50402[Other Products]
NCBI Official Full Name
emerin
NCBI Official Synonym Full Names
emerin
NCBI Official Symbol
EMD [Similar Products]
NCBI Official Synonym Symbols
STA; EDMD; LEMD5
[Similar Products]
NCBI Protein Information
emerin
UniProt Protein Name
Emerin
UniProt Gene Name
EMD [Similar Products]
UniProt Synonym Gene Names
EDMD; STA [Similar Products]
UniProt Entry Name
EMD_HUMAN
NCBI Summary for EMD
Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene. [provided by RefSeq, Jul 2008]
Research Articles on EMD
1. Study data revealed that low expression of emerin contributes not only to the oval shape of nuclei, but also to the enlargement in nuclear size in lung adenocarcinoma pathological specimens.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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