Delta-Sarcoglycan, Blocking Peptide

SGCD; sarcoglycan, delta (35kDa dystrophin-associated glycoprotein); 35DAG; CMD1L; DAGD; MGC22567; SG-delta; SGCDP; SGD; 35 kDa dystrophin-associated glycoprotein; 35kD dystrophin-associated glycoprotein; delta-SG; delta-sarcoglycan; dystrophin associated; Delta-SarcoglycanDefensin; Delta-Sarcoglycan (aa245-257)

For Research Use Only. Not for use in diagnostic procedures.

100ug of dried peptide

Shipped at ambient temperature, store at -20 degree C

Manufactured in an ISO 9001:2008 Certified Laboratory.

Small volumes of SGCD blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

28,750 Da

sarcoglycan delta

delta-sarcoglycan

Delta-sarcoglycan

Delta-SG; 35DAG  [Similar Products]

SGCD_HUMAN

The protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008]

SGCD: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. Defects in SGCD are the cause of limb-girdle muscular dystrophy type 2F (LGMD2F). LGMD2F is an autosomal recessive disorder. Defects in SGCD are the cause of cardiomyopathy dilated type 1L (CMD1L). Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death. Belongs to the sarcoglycan beta/delta/gamma/zeta family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Dystrophin complex

Chromosomal Location of Human Ortholog: 5q33-q34

Cellular Component: cytoplasm; cytoskeleton; dystrophin-associated glycoprotein complex; integral to membrane; plasma membrane; sarcoglycan complex; sarcolemma

Biological Process: cardiac muscle development; heart contraction; muscle cell development; muscle development

Disease: Cardiomyopathy, Dilated, 1l; Muscular Dystrophy, Limb-girdle, Type 2f

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