Full Product Name
CCL26 Antibody
Product Gene Name
anti-CCL26 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9Y258
Other Notes
Small volumes of anti-CCL26 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Western Blot (WB) of anti-CCL26 antibody
Western blot analysis CCL26 using COLO205 whole cell lysates
NCBI/Uniprot data below describe general gene information for CCL26. It may not necessarily be applicable to this product.
NCBI Accession #
NP_006063.1
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NCBI GenBank Nucleotide #
NM_006072.4
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UniProt Primary Accession #
Q9Y258
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UniProt Secondary Accession #
Q52LV8; A0N0Q5[Other Products]
UniProt Related Accession #
Q9Y258[Other Products]
Molecular Weight
10,648 Da
NCBI Official Full Name
C-C motif chemokine 26
NCBI Official Synonym Full Names
C-C motif chemokine ligand 26
NCBI Official Symbol
CCL26 [Similar Products]
NCBI Official Synonym Symbols
IMAC; TSC-1; MIP-4a; SCYA26; MIP-4alpha
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NCBI Protein Information
C-C motif chemokine 26
UniProt Protein Name
C-C motif chemokine 26
UniProt Synonym Protein Names
CC chemokine IMAC; Eotaxin-3; Macrophage inflammatory protein 4-alpha; MIP-4-alpha; Small-inducible cytokine A26; Thymic stroma chemokine-1; TSC-1
Protein Family
C-C motif chemokine
UniProt Gene Name
CCL26 [Similar Products]
UniProt Synonym Gene Names
SCYA26; MIP-4-alpha; TSC-1 [Similar Products]
NCBI Summary for CCL26
This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases. [provided by RefSeq, Jul 2008]
UniProt Comments for CCL26
Chemoattractant for eosinophils and basophils (PubMed:10415065, PubMed:10488147). Acts as a ligand for C-C chemokine receptor CCR3 which triggers Ca2+ mobilization in eosinophils (PubMed:10415065, PubMed:10488147, PubMed:11425309).
Research Articles on CCL26
1. Based on the ADEPT study data set, we report that airway mucosal expression of CCL26 was a robust discriminator of type 2 inflammation from healthy nonatopic subjects. Furthermore, airway mucosal CCL26 expression was best identified by using a panel of clinical biomarkers, including Feno values, bEOS counts, and expression of 2 novel markers, sCCL17 and sCCL26
Precautions
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Disclaimer
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