Product Name
Transient receptor potential cation channel subfamily V member 3 (Trpv3), Recombinant Protein
Full Product Name
Recombinant Mouse Transient receptor potential cation channel subfamily V member 3 (Trpv3), partial
Product Gene Name
Trpv3 recombinant protein
[Similar Products]
Product Synonym Gene Name
Trpv3[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q8K424
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Mus musculus (Mouse)
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Trpv3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Trpv3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_659567.2
[Other Products]
NCBI GenBank Nucleotide #
NM_145099.2
[Other Products]
UniProt Primary Accession #
Q8K424
[Other Products]
UniProt Secondary Accession #
Q5SV08[Other Products]
UniProt Related Accession #
Q8K424[Other Products]
Molecular Weight
90,663 Da
NCBI Official Full Name
transient receptor potential cation channel subfamily V member 3
NCBI Official Synonym Full Names
transient receptor potential cation channel, subfamily V, member 3
NCBI Official Symbol
Trpv3 [Similar Products]
NCBI Official Synonym Symbols
Nh; VRL3; AI644701; 1110036I10Rik
[Similar Products]
NCBI Protein Information
transient receptor potential cation channel subfamily V member 3
UniProt Protein Name
Transient receptor potential cation channel subfamily V member 3
Protein Family
Transient receptor potential cation channel subfamily
UniProt Gene Name
Trpv3 [Similar Products]
UniProt Synonym Gene Names
TrpV3 [Similar Products]
UniProt Comments for Trpv3
Putative receptor-activated non-selective calcium permeant cation channel. It is activated by innocuous (warm) temperatures and shows an increased response at noxious temperatures greater than 39 degrees Celsius. Activation exhibits an outward rectification. May associate with TRPV1 and may modulate its activity. Is a negative regulator of hair growth and cycling: TRPV3-coupled signaling suppresses keratinocyte proliferation in hair follicles and induces apoptosis and premature hair follicle regression (catagen) ().
Research Articles on Trpv3
1. These results suggest that TRPV4, TRPV3 and TRPM8 proteins, but not their ion channel activities are necessary for the induction of CIPs at 32 degrees C. Identification of proteins that differentially interact with these TRP channels at 37 degrees C and 32 degrees C would help elucidate the underlying mechanisms of CIP induction by hypothermia.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
