NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductas

Mouse NADH dehydrogenase [ubiquinone] iron-sulfur protein 7; mitochondrial (NDUFS7) ELISA kit; CI-20KD; FLJ45860; FLJ46880; MGC120002; MY017; PSST; NADH dehydrogenase [ubiquinone] iron-sulfur protein 7; mitochondrial; NADH-coenzyme Q reductase; NADH-ubiquinone oxidoreductase Fe-S protein 7; NADH; NADH dehydrogenase (ubiquinone) Fe-S protein 7; 20kDa (NADH-coenzyme Q reductase)

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

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Small volumes of NDUFS7 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9321344 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) (NDUFS7) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing NDUFS7. The ELISA analytical biochemical technique of the MBS9321344 kit is based on NDUFS7 antibody-NDUFS7 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NDUFS7 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NDUFS7. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

24,683 Da

NADH dehydrogenase (ubiquinone) Fe-S protein 7

NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial; NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial; CI-20kD; complex I-20kD; NADH-ubiquinone oxidoreductase 20 kDa subunit

NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

CI-20kD  [Similar Products]

NDUS7_MOUSE

NDUFS7: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Defects in NDUFS7 are a cause of Leigh syndrome (LS). LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions. Defects in NDUFS7 are a cause of mitochondrial complex I deficiency (MT-C1D). A disorder of the mitochondrial respiratory chain that causes a wide range of clinical disorders, from lethal neonatal disease to *****-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease. Belongs to the complex I 20 kDa subunit family.

Protein type: EC 1.6.99.3; Energy Metabolism - oxidative phosphorylation; EC 1.6.5.3; Mitochondrial; Oxidoreductase

Cellular Component: neuron projection; mitochondrion; cell soma; mitochondrial inner membrane; mitochondrial respiratory chain complex I

Molecular Function: NADH dehydrogenase (ubiquinone) activity; protease binding; 4 iron, 4 sulfur cluster binding; metal ion binding; iron-sulfur cluster binding; oxidoreductase activity; quinone binding; NADH dehydrogenase activity

Biological Process: mitochondrial respiratory chain complex I assembly; transport

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