Full Product Name
IRX4 Antibody (C-Term)
Product Synonym Names
Iroquois-class homeodomain protein IRX-4; Homeodomain protein IRXA3; Iroquois homeobox protein 4; IRX4; IRXA3
Product Gene Name
anti-IRX4 antibody
[Similar Products]
Product Synonym Gene Name
IRXA3[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P78413
Species Reactivity
Human, Mouse
Specificity
This IRX4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 107-141 amino acids from human IRX4.
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Antigen Type
Synthesized Peptide
Cellular Location
Nucleus.
Tissue Location
Predominantly expressed in cardiac ventricles.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-IRX4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-IRX4 antibody
Likely to be an important mediator of ventricular differentiation during cardiac development.
Product Categories/Family for anti-IRX4 antibody
New Antibodies; Primary Antibodies; Cardiovascular
Applications Tested/Suitable for anti-IRX4 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-IRX4 antibody
WB: 1:2000
Western Blot (WB) of anti-IRX4 antibody
All lanes : Anti-IRX4 Antibody (C-Term) at 1:2000 dilution
Lane 1: Jurkat whole cell lysate
Lane 2: human heart lysate
Lane 3: mouse brain lysate
Lane 4: mouse heart lysate
Lane 5: U-2OS whole cell lysate
Lysates/proteins at 20 ug per lane.
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : 54 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
NCBI/Uniprot data below describe general gene information for IRX4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001265561.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001278632.1
[Other Products]
UniProt Primary Accession #
P78413
[Other Products]
UniProt Secondary Accession #
Q2NL64; Q9UHR2; B2RMW5; D3DTC5; H1AFL0; H1AFL1[Other Products]
UniProt Related Accession #
P78413[Other Products]
Molecular Weight
54445 Da
NCBI Official Full Name
iroquois-class homeodomain protein IRX-4 isoform b
NCBI Official Synonym Full Names
iroquois homeobox 4
NCBI Official Symbol
IRX4 [Similar Products]
NCBI Official Synonym Symbols
IRXA3
[Similar Products]
NCBI Protein Information
iroquois-class homeodomain protein IRX-4
UniProt Protein Name
Iroquois-class homeodomain protein IRX-4
UniProt Synonym Protein Names
Homeodomain protein IRXA3; Iroquois homeobox protein 4
Protein Family
Iroquois-class homeodomain protein
UniProt Gene Name
IRX4 [Similar Products]
UniProt Synonym Gene Names
IRXA3 [Similar Products]
UniProt Comments for IRX4
IRX4: Likely to be an important mediator of ventricular differentiation during cardiac development. Belongs to the TALE/IRO homeobox family.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 5p15.33
Product References and Citations for anti-IRX4 antibody
Bruneau B.G.,et al.Dev. Biol. 217:266-277 (2000). Hansen L.,et al.Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases. Nguyen H.H.,et al.Hum. Mol. Genet. 21:2076-2085 (2012). Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. Lewis M.T.,et al.Submitted (MAR-1997) to the EMBL/GenBank/DDBJ databases.
Research Articles on IRX4
1. We independently validated IRX4 as a potential prostate cancer risk gene through cis-expression quantitative trait loci analysis of prostate cancer risk variants.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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