Sterile Alpha and TIR Motif-Containing Protein 1 (SARM1), ELISA Kit

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.

Small volumes of SARM1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9360436 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Sterile Alpha and TIR Motif-Containing Protein 1 (SARM1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SARM1. The ELISA analytical biochemical technique of the MBS9360436 kit is based on SARM1 antibody-SARM1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SARM1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SARM1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

75,337 Da

sterile alpha and TIR motif containing 1

sterile alpha and TIR motif-containing protein 1

Sterile alpha and TIR motif-containing protein 1

KIAA0524; SAMD2; SARM; MyD88-5; SAM domain-containing protein 2  [Similar Products]

SARM1_HUMAN

SARM1: Involved in innate immnune response. Acts as a negative regulator of TICAM1/TRIF-dependent Toll-like receptor signaling by inhibiting induction of TLR3- and TLR4-dependent genes. Specifically blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction, without affecting the MYD88- dependent pathway or non-TLR signaling. Negative regulator of NF- kappa-B and IRF activation. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 17q11

Cellular Component: axon; cell junction; cytoplasm; cytosol; dendrite; extrinsic to mitochondrial outer membrane; microtubule; mitochondrion; synapse

Biological Process: innate immune response; MyD88-independent toll-like receptor signaling pathway; regulation of apoptosis; regulation of dendrite morphogenesis; response to glucose stimulus; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor signaling pathway

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