Full Product Name
MGME1 Antibody - C-terminal region
Product Gene Name
anti-MGME1 antibody
[Similar Products]
Product Synonym Gene Name
DDK1; MTDPS11; C20orf72; bA504H3.4[Similar Products]
Antibody/Peptide Pairs
MGME1 peptide (MBS3246178) is used for blocking the activity of MGME1 antibody (MBS3221444)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: CGLIVVAYKD GSPAHPHFMD AELCSQYWTK WLLRLEEYTE KKKNQNIQKP
3D Structure
ModBase 3D Structure for Q9BQP7
Purity/Purification
Affinity purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human C20ORF72
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-MGME1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-MGME1 antibody
The protein encoded by this gene is a nuclear-encoded mitochondrial protein necessary for the maintenance of mitochondrial genome synthesis. The encoded protein is a RecB-type exonuclease and primarily cleaves single-stranded DNA. Defects in this gene have been associated with mitochondrial DNA depletion syndrome-11. Three transcript variants encoding different isoforms have been found for this gene.
Product Categories/Family for anti-MGME1 antibody
Polyclonal; Cell Biology; Mitochondria; Disease Related;
Applications Tested/Suitable for anti-MGME1 antibody
Western Blot (WB)
Western Blot (WB) of anti-MGME1 antibody
Host: Rabbit
Target Name: C20ORF72
Sample Tissue: Human 786-0 Whole Cell lysates
Antibody Dilution: 1ug/ml
NCBI/Uniprot data below describe general gene information for MGME1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_443097.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001310338.1
[Other Products]
UniProt Primary Accession #
Q9BQP7
[Other Products]
UniProt Related Accession #
Q9BQP7[Other Products]
NCBI Official Full Name
mitochondrial genome maintenance exonuclease 1 isoform 2
NCBI Official Synonym Full Names
mitochondrial genome maintenance exonuclease 1
NCBI Official Symbol
MGME1 [Similar Products]
NCBI Official Synonym Symbols
DDK1; MTDPS11; C20orf72; bA504H3.4
[Similar Products]
NCBI Protein Information
mitochondrial genome maintenance exonuclease 1
UniProt Protein Name
Mitochondrial genome maintenance exonuclease 1
Protein Family
Mitochondrial genome maintenance exonuclease
UniProt Gene Name
MGME1 [Similar Products]
UniProt Synonym Gene Names
C20orf72; DDK1 [Similar Products]
UniProt Entry Name
MGME1_HUMAN
NCBI Summary for MGME1
The protein encoded by this gene is a nuclear-encoded mitochondrial protein necessary for the maintenance of mitochondrial genome synthesis. The encoded protein is a RecB-type exonuclease and primarily cleaves single-stranded DNA. Defects in this gene have been associated with mitochondrial DNA depletion syndrome-11. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015]
Research Articles on MGME1
1. MGME1 is part of a termination complex acting at the end of the D-loop region where it modulates mtDNA replication and H-strand transcription termination
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
