Product Name
GTPase HRas (Hras1), Recombinant Protein
Full Product Name
Recombinant Mouse GTPase HRas (Hras1)
Product Gene Name
Hras1 recombinant protein
[Similar Products]
Product Synonym Gene Name
Hras1[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-186aa, full length protein
Sequence
MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG QEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHQYREQI KRVKDSDDVP MVLVGNKCDL AARTVESRQA QDLARSYGIP YIETSAKTRQ GVEDAFYTLV REIRQHKLRK LNPPDESGPG CMSCKC
3D Structure
ModBase 3D Structure for Q61411
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Hras1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Hras1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001123915.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001130443.1
[Other Products]
UniProt Primary Accession #
Q61411
[Other Products]
UniProt Secondary Accession #
Q6P716; Q80WD2; Q811B9; F7BIB2[Other Products]
UniProt Related Accession #
Q61411[Other Products]
Molecular Weight
20,880 Da
NCBI Official Full Name
GTPase HRas isoform 1
NCBI Official Synonym Full Names
Harvey rat sarcoma virus oncogene
NCBI Official Symbol
Hras [Similar Products]
NCBI Official Synonym Symbols
ras; H-ras; Hras1; Kras2; Ha-ras; Hras-1; c-H-ras; c-rasHa; c-Ha-ras; Harvey-ras
[Similar Products]
NCBI Protein Information
GTPase HRas
UniProt Protein Name
GTPase HRas
UniProt Synonym Protein Names
H-Ras-1; Transforming protein p21; c-H-ras; p21ras
UniProt Gene Name
Hras [Similar Products]
UniProt Synonym Gene Names
Hras1 [Similar Products]
UniProt Comments for Hras1
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
Research Articles on Hras1
1. Loss of wild-type Hras promotes the earliest stages of pancreatic tumorigenesis, and moreover results in more rapid progression of the disease. As such, mechanisms leading to activation of wild-type Ras proteins, including but not limited to redox-dependent reactions, may influence the development of pancreatic cancer.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
