Product Name
SAM domain and HD domain 1 (SAMHD1), Polyclonal Antibody
Full Product Name
Rabbit anti-human SAM domain and HD domain 1 polyclonal Antibody
Product Synonym Names
SAM domain and HD domain 1; SAMHD1; DCIP; HDDC1; MOP-5; SBBI88
Product Gene Name
anti-SAMHD1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-86212 / sc-86213
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-SAMHD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-SAMHD1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
NCBI/Uniprot data below describe general gene information for SAMHD1. It may not necessarily be applicable to this product.
NCBI Accession #
AAH36450.1
[Other Products]
UniProt Secondary Accession #
Q5JXG8; Q8N491; Q9H004; Q9H005; Q9H3U9; B4E2A5; E1P5V2[Other Products]
UniProt Related Accession #
Q9Y3Z3[Other Products]
Molecular Weight
68,122 Da[Similar Products]
NCBI Official Full Name
SAM domain and HD domain 1
NCBI Official Synonym Full Names
SAM domain and HD domain 1
NCBI Official Symbol
SAMHD1 [Similar Products]
NCBI Official Synonym Symbols
DCIP; CHBL2; HDDC1; MOP-5; SBBI88
[Similar Products]
NCBI Protein Information
deoxynucleoside triphosphate triphosphohydrolase SAMHD1; dNTPase; monocyte protein 5; dendritic cell-derived IFNG-induced protein; SAM domain and HD domain-containing protein 1
UniProt Protein Name
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
UniProt Synonym Protein Names
Dendritic cell-derived IFNG-induced protein; DCIP; Monocyte protein 5; MOP-5; SAM domain and HD domain-containing protein 1
Protein Family
Deoxynucleoside triphosphate triphosphohydrolase
UniProt Gene Name
SAMHD1 [Similar Products]
UniProt Synonym Gene Names
MOP5; dNTPase; DCIP; MOP-5 [Similar Products]
UniProt Entry Name
SAMH1_HUMAN
NCBI Summary for SAMHD1
This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010]
UniProt Comments for SAMHD1
SAMHD1: a protein induced by interferon gamma.
Protein type: EC 3.1.4.-
Chromosomal Location of Human Ortholog: 20pter-q12
Cellular Component: nucleoplasm; plasma membrane; intracellular; nucleus
Molecular Function: protein binding; nucleic acid binding; dGTPase activity; zinc ion binding; RNA binding; dGTP binding
Biological Process: dGTP catabolic process; dATP catabolic process; cytokine and chemokine mediated signaling pathway; immune response; defense response to virus; regulation of innate immune response; protein homotetramerization
Disease: Chilblain Lupus 2; Aicardi-goutieres Syndrome 5
Research Articles on SAMHD1
1. these findings identify a direct relationship between control of the cell cycle by CDK6 and SAMHD1 activity, which is important for replication of lentiviruses, as well as other viruses whose replication may be regulated by intracellular dNTP availability.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
