Product Name
Myosin-binding protein C (Mybpc3), Polyclonal Antibody
Full Product Name
Rabbit anti-rat Myosin-binding protein C, cardiac-type polyclonal Antibody, FITC
Product Synonym Names
Cardiac MyBP-C; C-protein; cardiac muscle isoform; Mybpc3;
Product Gene Name
anti-Mybpc3 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P56741
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-Mybpc3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-Mybpc3 antibody
Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.
Applications Tested/Suitable for anti-Mybpc3 antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for Mybpc3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001099960.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001106490.1
[Other Products]
UniProt Primary Accession #
P56741
[Other Products]
UniProt Related Accession #
P56741[Other Products]
Molecular Weight
140,762 Da[Similar Products]
NCBI Official Full Name
myosin-binding protein C, cardiac-type
NCBI Official Synonym Full Names
myosin binding protein C, cardiac
NCBI Official Symbol
Mybpc3 [Similar Products]
NCBI Protein Information
myosin-binding protein C, cardiac-type
UniProt Protein Name
Myosin-binding protein C, cardiac-type
UniProt Synonym Protein Names
C-protein, cardiac muscle isoform
Protein Family
Myosin-binding protein
UniProt Gene Name
Mybpc3 [Similar Products]
UniProt Synonym Gene Names
Cardiac MyBP-C [Similar Products]
UniProt Entry Name
MYPC_RAT
UniProt Comments for Mybpc3
MYBPC3: Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. Belongs to the immunoglobulin superfamily. MyBP family.
Protein type: Myosin-binding
Cellular Component: A band; myofibril; sarcomere; striated muscle thick filament
Molecular Function: actin binding; identical protein binding; metal ion binding; myosin binding; myosin heavy chain binding; structural constituent of muscle
Biological Process: cardiac muscle contraction; cell adhesion; heart morphogenesis; muscle contraction; myosin filament assembly; regulation of heart contraction; regulation of heart rate; regulation of striated muscle contraction; sarcomere organization; ventricular cardiac muscle morphogenesis
Research Articles on Mybpc3
1. Data show that expression of mutant protein cMyBP-C (cMyBP-C(C10mut)) in cultured ***** rat cardiomyocytes led to improper localization and contractile dysfunction.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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