Product Name
SAMHD1, cDNA Clone
Full Product Name
SAMHD1 cDNA Clone
Product Gene Name
SAMHD1 cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgcagcgag ccgattccga gcagccctcc aagcgtcccc gttgcgatga cagcccgaga accccctcaa acaccccttc cgcagaggca gactggtccc cgggcctgga actccatccc gactacaaga catggggtcc ggagcaggtg tgctccttcc tcaggcgcgg tggctttgaa gagccggtgc tgctgaagaa catccgagaa aatgaaatca caggcgcatt actgccttgt cttgatgagt ctcgttttga aaatcttgga gtaagttcct tgggggagag gaagaagctg cttagttata tccagcgatt ggttcaaatc cacgttgata caatgaaggt aattaatgat cctatccatg gccacattga gctccaccct ctcctcgtcc gaatcattga tacacctcaa tttcaacgtc ttcgatacat caaacagctg ggaggtggtt actatgtttt tccaggagct tcgcacaatc gatttgagca tagtctaggg gtggggtatc tagcaggatg tctagttcac gcactgggtg aaaaacaacc agagctgcag ataagtgaac gagatgttct ctgtgttcag attgctggac tttgtcatga tctcggtcat gggccatttt ctcacatgtt tgatggacga tttattccac ttgctcgccc ggaggtgaaa tggacgcatg aacaaggctc agttatgatg tttgagcacc ttattaattc taatggaatt aagcctgtca tggaacaata tggtctcatc cctgaagaag atatttgctt tataaaggaa caaattgtag gaccacttga atcacctgta gaagattcat tgtggccata taaagggcgt cctgaaaaca aaagcttcct ttatgagata gtatctaata aaagaaatgg cattgatgtg gacaaatggg attattttgc cagggactgc catcatcttg gaatccaaaa taattttgat tacaagcgct ttattaagtt tgcccgtgtc tgtgaagtag acaatgagtt gcgtatttgt gctagagata aggaagttgg aaatctgtat gacatgttcc acactcgcaa ctctttacac cgtagagctt atcaacacaa agttggcaac attattgata caatgattac agatgctttc ctcaaagcag atgactacat agagattaca ggtgctggag aaaaaaagta tcgcatttct acagcaattg acgacatgga agcctatact aagctgacag ataacatttt tctggagatt ttatactcta ctgatcccaa attgaaagac gcacgagaga ttttaaaaca aattgaatac cgtaatctat tcaagtatgt gggtgagacg cagccaacag gacaaataaa gattaaaagg gaggactatg aatctcttcc aaaagaggtt gccagtgcta aacccaaagt attgctagac gtgaaactga aggctgaaga ttttatagtg gatgttatca acatggatta tggaatgcaa gaaaagaatc caattgatca tgttagcttc tattgtaaga ctgcccccaa cagagcaatc aggattacta aaaaccaggt ttcacaactt ctgccagaga aatttgtaga gcagctgatt cgagtatatt gtaagaaggt ggacagaaag agtttgtatg ccgcaagaca atattttgtt cagtggtgtg cagacagaaa tttcaccaag ccgcaggatg gcgatgttat agccccactc ataacacctc aaaaaaagga atggaacgac agtacttcag tccaaaatcc aactcgcctc cgagaagcat ccaaaagcag agtccagctt tttaaagatg acccaatgtg a
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of SAMHD1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for SAMHD1. It may not necessarily be applicable to this product.
NCBI Accession #
BC036450
[Other Products]
UniProt Secondary Accession #
Q5JXG8; Q8N491; Q9H004; Q9H005; Q9H3U9; B4E2A5; E1P5V2[Other Products]
UniProt Related Accession #
Q9Y3Z3[Other Products]
Molecular Weight
68,122 Da
NCBI Official Full Name
Homo sapiens SAM domain and HD domain 1, mRNA
NCBI Official Synonym Full Names
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
NCBI Official Symbol
SAMHD1 [Similar Products]
NCBI Official Synonym Symbols
DCIP; CHBL2; HDDC1; MOP-5; SBBI88
[Similar Products]
NCBI Protein Information
deoxynucleoside triphosphate triphosphohydrolase SAMHD1
UniProt Protein Name
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
UniProt Synonym Protein Names
Dendritic cell-derived IFNG-induced protein; DCIP; Monocyte protein 5; MOP-5; SAM domain and HD domain-containing protein 1
Protein Family
Deoxynucleoside triphosphate triphosphohydrolase
UniProt Gene Name
SAMHD1 [Similar Products]
UniProt Synonym Gene Names
MOP5; dNTPase; DCIP; MOP-5 [Similar Products]
UniProt Entry Name
SAMH1_HUMAN
NCBI Summary for SAMHD1
This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010]
UniProt Comments for SAMHD1
SAMHD1: a protein induced by interferon gamma.
Protein type: EC 3.1.4.-
Chromosomal Location of Human Ortholog: 20pter-q12
Cellular Component: nucleoplasm; nucleus; plasma membrane
Molecular Function: dGTP binding; dGTPase activity; nucleic acid binding; protein binding; RNA binding; zinc ion binding
Biological Process: dATP catabolic process; defense response to virus; dGTP catabolic process; protein homotetramerization; regulation of innate immune response
Disease: Aicardi-goutieres Syndrome 5; Chilblain Lupus 2
Research Articles on SAMHD1
1. Interferonstimulated gene factor 3 complex, which consists of STAT1, STAT2 and IRF9, is required for the induction of SAMHD1 expression by IFN-alpha in SMMC-7721 cells.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
