Full Product Name
NR2E3 Antibody, Biotin conjugated
Product Synonym Names
Photoreceptor-specific nuclear receptor; Nuclear receptor subfamily 2 group E member 3; Retina-specific nuclear receptor; NR2E3; PNR; RNR
Product Gene Name
anti-NR2E3 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9Y5X4
Purity/Purification
>95%, Protein G purified
Immunogen
Recombinant Human Photoreceptor-specific nuclear receptor protein (112-222AA)
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-NR2E3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-NR2E3 antibody
Orphan nuclear receptor of retinal photoreceptor cells. Transcriptional factor that is an activator of rod development and repressor of cone development. Binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. Enhances rhodopsin expression. Represses M- and S-cone opsin expression.
Product Categories/Family for anti-NR2E3 antibody
Neuroscience; Signal transduction
Applications Tested/Suitable for anti-NR2E3 antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for NR2E3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_055064.1
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NCBI GenBank Nucleotide #
NM_014249.3
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UniProt Primary Accession #
Q9Y5X4
[Other Products]
UniProt Secondary Accession #
Q9UHM4; B6ZGU0[Other Products]
UniProt Related Accession #
Q9Y5X4[Other Products]
Molecular Weight
39,638 Da
NCBI Official Full Name
photoreceptor-specific nuclear receptor isoform b
NCBI Official Synonym Full Names
nuclear receptor subfamily 2 group E member 3
NCBI Official Symbol
NR2E3 [Similar Products]
NCBI Official Synonym Symbols
PNR; RNR; rd7; ESCS; RP37
[Similar Products]
NCBI Protein Information
photoreceptor-specific nuclear receptor
UniProt Protein Name
Photoreceptor-specific nuclear receptor
UniProt Synonym Protein Names
Nuclear receptor subfamily 2 group E member 3; Retina-specific nuclear receptor
Protein Family
Photoreceptor-specific nuclear receptor
UniProt Gene Name
NR2E3 [Similar Products]
UniProt Synonym Gene Names
PNR; RNR [Similar Products]
NCBI Summary for NR2E3
This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in *****s. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
UniProt Comments for NR2E3
Orphan nuclear receptor of retinal photoreceptor cells. Transcriptional factor that is an activator of rod development and repressor of cone development. Binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. Enhances rhodopsin expression. Represses M- and S-cone opsin expression.
Research Articles on NR2E3
1. Photoreceptor-specific nuclear receptor (PNR/NR2E3) and Tailless homolog (TLX/NR2E1) are human orthologs of the NR2E group.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
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