Product Name
SEC23A, Polyclonal Antibody
Full Product Name
SEC23A Antibody
Product Synonym Names
Protein transport protein Sec23A; SEC23-related protein A; SEC23A
Product Gene Name
anti-SEC23A antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q15436
Purity/Purification
>95%, Protein G purified
Immunogen
Recombinant Human Protein transport protein Sec23A protein (424-569AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
Conjugation
Non-conjugated
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-SEC23A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SEC23A antibody
Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex.
Applications Tested/Suitable for anti-SEC23A antibody
ELISA (EIA), Immunofluorescence (IF)
Application Notes for anti-SEC23A antibody
IF: 1: 50-1: 200
Immunofluorescence (IF) of anti-SEC23A antibody
Immunofluorescent analysis of Hela cells using MBS7050212 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
NCBI/Uniprot data below describe general gene information for SEC23A. It may not necessarily be applicable to this product.
NCBI Accession #
NP_006355.2
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NCBI GenBank Nucleotide #
NM_006364.3
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UniProt Primary Accession #
Q15436
[Other Products]
UniProt Secondary Accession #
Q8NE16; B2R5P4; B3KXI2[Other Products]
UniProt Related Accession #
Q15436[Other Products]
Molecular Weight
63,101 Da
NCBI Official Full Name
protein transport protein Sec23A
NCBI Official Synonym Full Names
Sec23 homolog A, coat complex II component
NCBI Official Symbol
SEC23A [Similar Products]
NCBI Official Synonym Symbols
CLSD
[Similar Products]
NCBI Protein Information
protein transport protein Sec23A
UniProt Protein Name
Protein transport protein Sec23A
UniProt Synonym Protein Names
SEC23-related protein A
Protein Family
Protein transport protein
UniProt Gene Name
SEC23A [Similar Products]
UniProt Entry Name
SC23A_HUMAN
NCBI Summary for SEC23A
The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family. It is part of a protein complex and found in the ribosome-free transitional face of the endoplasmic reticulum (ER) and associated vesicles. This protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The encoded protein is suggested to play a role in the ER-Golgi protein trafficking. [provided by RefSeq, Jul 2008]
UniProt Comments for SEC23A
SEC23A: Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex. COPII is composed of at least five proteins: the Sec23/24 complex, the Sec13/31 complex and Sar1. Interacts with SEC23IP. Interacts with HTR4. Interacts with SLC6A4. Interacts with SEC16A. Belongs to the SEC23/SEC24 family. SEC23 subfamily.
Protein type: Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 14q21.1
Cellular Component: cytosol; endoplasmic reticulum; endoplasmic reticulum membrane
Molecular Function: protein binding
Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; antigen processing and presentation of peptide antigen via MHC class I; COPII coating of Golgi vesicle; ER to Golgi vesicle-mediated transport; vesicle-mediated transport
Disease: Craniolenticulosutural Dysplasia
Research Articles on SEC23A
1. ALG-2 attenuates COPII budding in vitro and stabilizes the Sec23/Sec31A complex.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
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