Product Name
Matrix Extracellular Phosphoglycoprotein (MEPE), ELISA Kit
Full Product Name
Cavy Matrix Extracellular Phosphoglycoprotein ELISA Kit
Product Gene Name
MEPE elisa kit
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
Chromosome Location
Chromosome: 4; NC_000004.11 (88742563..88767969). Location: 4q21.1
3D Structure
ModBase 3D Structure for Q9NQ76
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of MEPE elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for MEPE purchase
MBS039004 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Matrix Extracellular Phosphoglycoprotein (MEPE) ELISA Kit target analytes in
biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MEPE. The ELISA analytical biochemical technique of the MBS039004 kit is based on MEPE antibody-MEPE antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MEPE antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MEPE. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for MEPE. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001171626.1
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NCBI GenBank Nucleotide #
NM_001184697.1
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UniProt Primary Accession #
Q9NQ76
[Other Products]
UniProt Secondary Accession #
A1A4X9; A8MTA3; D2CFR4; F5H5C5[Other Products]
UniProt Related Accession #
Q9NQ76[Other Products]
Molecular Weight
58,419 Da
NCBI Official Full Name
matrix extracellular phosphoglycoprotein isoform b
NCBI Official Synonym Full Names
matrix extracellular phosphoglycoprotein
NCBI Official Symbol
MEPE [Similar Products]
NCBI Official Synonym Symbols
OF45
[Similar Products]
NCBI Protein Information
matrix extracellular phosphoglycoprotein; osteoblast/osteocyte factor 45; matrix, extracellular phosphoglycoprotein with ASARM motif (bone)
UniProt Protein Name
Matrix extracellular phosphoglycoprotein
UniProt Synonym Protein Names
Osteoblast/osteocyte factor 45
Protein Family
Matrix extracellular phosphoglycoprotein
UniProt Gene Name
MEPE [Similar Products]
UniProt Synonym Gene Names
OF45 [Similar Products]
UniProt Entry Name
MEPE_HUMAN
NCBI Summary for MEPE
This gene encodes a secreted calcium-binding phosphoprotein that belongs to the small integrin-binding ligand, N-linked glycoprotein (SIBLING) family of proteins. Members of this family are components of the extracellular matrix of bone and dentin and regulate bone mineralization. Deficiency of a similar protein in mouse results in increased bone mass. Mice lacking this gene are resistant to aging-related trabecular bone loss. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
UniProt Comments for MEPE
MEPE: Promotes renal phosphate excretion and modulates mineralization. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 4q21.1
Cellular Component: proteinaceous extracellular matrix
Molecular Function: protein binding; extracellular matrix structural constituent
Biological Process: negative regulation of bone mineralization; biomineral formation; regulation of bone remodeling; skeletal development
Research Articles on MEPE
1. results indicated that MEPE appeared to play an important positive role in proliferation and osteogenesis differentiation of DPCs through interaction with downstream signals.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
