Centrosomal protein of 57 kDa (CEP57), ELISA Kit

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C.

We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.

Small volumes of Cep57 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS7232385 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Centrosomal protein of 57 kDa (CEP57) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Cep57. The ELISA analytical biochemical technique of the MBS7232385 kit is based on Cep57 antibody-Cep57 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Cep57 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Cep57. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Epigenetics and Nuclear Signaling

39,996 Da[Similar Products]

centrosomal protein 57

centrosomal protein of 57 kDa; translokin; testis-specific protein 57

Centrosomal protein of 57 kDa

Kiaa0092; Tsp57; Cep57  [Similar Products]

CEP57_MOUSE

CEP57: Centrosomal protein which may be required for microtubule attachment to centrosomes. May act by forming ring- like structures around microtubules. Mediates nuclear translocation and mitogenic activity of the internalized growth factor FGF2. Defects in CEP57 are the cause of mosaic variegated aneuploidy syndrome type 2 (MVA2). MVA2 is a severe developmental disorder characterized by mosaic aneuploidies, predominantly trisomies and monosomies, involving multiple different chromosomes and tissues. Affected individuals typically present with severe intrauterine growth retardation and microcephaly. Eye anomalies, mild dysmorphism, variable developmental delay, and a broad spectrum of additional congenital abnormalities and medical conditions may also occur. The risk of malignancy is high, with rhabdomyosarcoma, Wilms tumor and leukemia reported in several cases. Belongs to the translokin family. 4 isoforms of the human protein are produced by alternative splicing.

Cellular Component: microtubule cytoskeleton; nucleoplasm; Golgi apparatus; microtubule; centrosome; cytoskeleton; cell; cytoplasm; intracellular; nucleus

Molecular Function: identical protein binding; gamma-tubulin binding; protein binding; protein homodimerization activity; fibroblast growth factor binding; microtubule binding

Biological Process: fibroblast growth factor receptor signaling pathway; protein import into nucleus, translocation; protein homooligomerization

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