Full Product Name
HXD13 Polyclonal Antibody
Product Synonym Names
Homeobox protein Hox-D13; Homeobox protein Hox-4I; HOXD13; HOX4I
Product Gene Name
anti-HXD13 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P35453
Species Reactivity
Human, Mouse
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-HXD13 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-HXD13 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-HXD13 antibody
WB: 1:500-2000
ELISA: 1:5000-20000
NCBI/Uniprot data below describe general gene information for HXD13. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000514.2
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NCBI GenBank Nucleotide #
NM_000523.3
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UniProt Primary Accession #
P35453
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UniProt Related Accession #
P35453[Other Products]
NCBI Official Full Name
homeobox protein Hox-D13
NCBI Official Synonym Full Names
homeobox D13
NCBI Official Symbol
HOXD13 [Similar Products]
NCBI Official Synonym Symbols
BDE; SPD; BDSD; SPD1; HOX4I
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NCBI Protein Information
homeobox protein Hox-D13
UniProt Protein Name
Homeobox protein Hox-D13
UniProt Synonym Protein Names
Homeobox protein Hox-4I
UniProt Gene Name
HOXD13 [Similar Products]
UniProt Synonym Gene Names
HOX4I [Similar Products]
NCBI Summary for HXD13
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. Mutations in this particular gene cause synpolydactyly. [provided by RefSeq, Jul 2008]
UniProt Comments for HXD13
Sequence-specific transcription factor that binds gene promoters and activates their transcription (PubMed:24789103). Part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis ().
Research Articles on HXD13
1. this study revealed that HOXB9, HOXB13, and HOXD13 were upregulated and may play important roles in laryngeal squamous cell carcinoma (LSCC). Moreover, HOXB9 may serve as a novel marker of poor prognosis and a potential therapeutic target in LSCC patients.
Precautions
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Disclaimer
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