Product Name
C6, cDNA Clone
Popular Item
Full Product Name
C6 cDNA Clone
Product Gene Name
C6 cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggccagac gctctgtctt gtacttcatc ctgctgaatg ctctgatcaa caagggccaa gcctgcttct gtgatcacta tgcatggact cagtggacca gctgctcaaa aacttgcaat tctggaaccc agagcagaca cagacaaata gtagtagata agtactacca ggaaaacttt tgtgaacaga tttgcagcaa gcaggagact agagaatgta actggcaaag atgccccatc aactgcctcc tgggagattt tggaccatgg tcagactgtg acccttgtat tgaaaaacag tctaaagtta gatctgtctt gcgtcccagt cagtttgggg gacagccatg cactgagcct ctggtagcct ttcaaccatg cattccatct aagctctgca aaattgaaga ggctgactgc aagaataaat ttcgctgtga cagtggccgc tgcattgcca gaaagttaga atgcaatgga gaaaatgact gtggagacaa ttcagatgaa agggactgtg ggaggacaaa ggcagtatgc acacggaagt ataatcccat ccctagtgta cagttgatgg gcaatgggtt tcattttctg gcaggagagc ccagaggaga agtccttgat aactctttca ctggaggaat atgtaaaact gtcaaaagca gtaggacaag taatccatac cgtgttccgg ccaatctgga aaatgtcggc tttgaggtac aaactgcaga agatgacttg aaaacagatt tctacaagga tttaacttct cttggacaca atgaaaatca acaaggctca ttctcaagtc agggggggag ctctttcagt gtaccaattt tttattcctc aaagagaagt gaaaatatca accataattc tgccttcaaa caagccattc aagcctctca caaaaaggat tctagtttta ttaggatcca taaagtgatg aaagtcttaa acttcacaac gaaagctaaa gatctgcacc tttctgatgt ctttttgaaa gcacttaacc atctgcctct agaatacaac tctgctttgt acagccgaat attcgatgac tttgggactc attacttcac ctctggctcc ctgggaggcg tgtatgacct tctctatcag tttagcagtg aggaactaaa gaactcaggt ttaaccgagg aagaagccaa acactgtgtc aggattgaaa caaagaaacg cgttttattt gctaagaaaa caaaagtgga acataggtgc accaccaaca agctgtcaga gaaacatgaa ggttcattta tacagggagc agagaaatcc atatccctga ttcgaggtgg aaggagtgaa tatggagcag ctttggcatg ggagaaaggg agctctggtc tggaggagaa gacattttct gagtggttag aatcagtgaa ggaaaatcct gctgtgattg actttgagct tgcccccatc gtggacttgg taagaaacat cccctgtgca gtgacaaaac ggaacaacct caggaaagct ttgcaagagt atgcagccaa gttcgatcct tgccagtgtg ctccatgccc taataatggc cgacccaccc tctcagggac tgaatgtctg tgtgtgtgtc agagtggcac ctatggtgag aactgtgaga aacagtctcc agattataaa tccaatgcag tagacggaca gtggggttgt tggtcttcct ggagtacctg tgatgctact tataagagat cgagaacccg agaatgcaat aatcctgccc cccaacgagg agggaaacgc tgtgaggggg agaagcgaca agaggaagac tgcacatttt caatcatgga aaacaatgga caaccatgta tcaatgatga tgaagaaatg aaagaggtcg atcttcctga gatagaagca gattccgggt gtcctcagcc agttcctcca gaaaatggat ttatccggaa tgaaaagcaa ctatacttgg ttggagaaga tgttgaaatt tcatgcctta ctggctttga aactgttgga taccagtact tcagatgctt accagacggg acctggagac aaggggatgt ggaatgccaa cggacggagt gcatcaagcc agttgtgcag gaagtcctga caattacacc atttcagaga ttgtatagaa ttggtgaatc cattgagcta acttgcccca aaggctttgt tgttgctggg ccatcaaggt acacatgcca ggggaattcc tggacaccac ccatttcaaa ctctctcacc tgtgaaaaag atactctaac aaaattaaaa ggccattgtc agctgggaca gaaacaatca ggatctgaat gcatttgtat gtctccagaa gaagactgta gccatcattc agaagatctc tgtgtgtttg acacagactc caacgattac tttacttcac ccgcttgtaa gtttttggct gagaaatgtt taaataatca gcaactccat tttctacata ttggttcctg ccaagacggc cgccagttag aatggggtct tgaaaggaca agactttcat ccaacagcac aaagaaagaa tcctgtggct atgacacctg ctatgactgg gaaaaatgtt cagcctccac ttccaaatgt gtctgcctat tgcccccaca gtgcttcaag ggtggaaacc aactctactg tgtcaaaatg ggatcatcaa caagtgagaa aacattgaac atctgtgaag tgggaactat aagatgtgca aacaggaaga tggaaatact gcatcctgga aagtgtttgg cctag
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of C6 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for C6. It may not necessarily be applicable to this product.
NCBI Accession #
BC035723
[Other Products]
UniProt Related Accession #
P13671[Other Products]
Molecular Weight
104,786 Da
NCBI Official Full Name
Homo sapiens complement component 6, mRNA
NCBI Official Synonym Full Names
complement C6
NCBI Official Symbol
C6 [Similar Products]
NCBI Protein Information
complement component C6
UniProt Protein Name
Complement component C6
Protein Family
Complement component
UniProt Gene Name
C6 [Similar Products]
UniProt Entry Name
CO6_HUMAN
NCBI Summary for C6
This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.[provided by RefSeq, Nov 2012]
UniProt Comments for C6
C6: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. Defects in C6 are the cause of complement component 6 deficiency (C6D). A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis. Belongs to the complement C6/C7/C8/C9 family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 5p13
Cellular Component: extracellular region
Molecular Function: protein binding
Biological Process: complement activation; regulation of complement activation
Disease: Complement Component 6 Deficiency
Research Articles on C6
1. Complement C5b-9 complex sensitizes 661W photoreceptor cells to both apoptosis and necroptosis.
Precautions
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Disclaimer
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