Product Name
Actin Alpha 1 (ACTC1), Polyclonal Antibody
Full Product Name
Cy3-Linked Anti-Actin Alpha 1, Cardiac Muscle (ACTC1) Polyclonal Antibody
Product Synonym Names
ACTC; CMD1R; CMD1-R; ACT-a1
Product Gene Name
anti-ACTC1 antibody
[Similar Products]
Matching Pairs
Unconjugated Antibody: Actin Alpha 1 (ACTC1) (MBS2034681)
Cy3 Conjugated Antibody: Actin Alpha 1 (ACTC1) (MBS2108652)
Matching Pairs
Antibody: Actin Alpha 1 (ACTC1) (MBS2108652)
Antigen: Actin Alpha 1, Cardiac Muscle (ACTC1) (MBS2018757)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Asp156~Gly 368
3D Structure
ModBase 3D Structure for P68032
Species Reactivity
Human, Mouse
Specificity
The antibody is a Rabbit polyclonal antibody raised against ACTC1 Polyclonal Antibody. It has been selected for its ability to recognize ACTC1 Polyclonal Antibody in immunohistochemical staining and western blotting.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Concentration
200ug/ml (lot specific)
Preparation and Storage
Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.
Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customerâs specifications, please inquire.
Other Notes
Small volumes of anti-ACTC1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ACTC1 antibody
Western Blot (WB)
Application Notes for anti-ACTC1 antibody
Loading Control of WB.
NCBI/Uniprot data below describe general gene information for ACTC1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_005150.1
[Other Products]
NCBI GenBank Nucleotide #
NM_005159.4
[Other Products]
UniProt Primary Accession #
P68032
[Other Products]
UniProt Related Accession #
P68032[Other Products]
NCBI Official Full Name
actin, alpha cardiac muscle 1
NCBI Official Synonym Full Names
actin alpha cardiac muscle 1
NCBI Official Symbol
ACTC1 [Similar Products]
NCBI Official Synonym Symbols
ACTC; ASD5; CMD1R; CMH11; LVNC4
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NCBI Protein Information
actin, alpha cardiac muscle 1
UniProt Protein Name
Actin, alpha cardiac muscle 1
UniProt Synonym Protein Names
Alpha-cardiac actin
UniProt Gene Name
ACTC1 [Similar Products]
UniProt Synonym Gene Names
ACTC [Similar Products]
UniProt Entry Name
ACTC_HUMAN
NCBI Summary for ACTC1
Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). [provided by RefSeq, Jul 2008]
Research Articles on ACTC1
1. These findings suggest that the familial ostium secundum atrial septal defect (ASDII)may be a result of an ACTC1 3'UTR gain-of-function mutation caused by the introduction of a new miR-139-5p target site. Our results provide the first evidence of a pathogenic mutation in the ACTC1 3'UTR that may be associated with familial isolated ASDII.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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