Actin, Alpha cardiac muscle 1 (ACTC1), ELISA Kit

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C.

We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.

Small volumes of ACTC1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS7225450 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Actin, Alpha cardiac muscle 1 (ACTC1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ACTC1. The ELISA analytical biochemical technique of the MBS7225450 kit is based on ACTC1 antibody-ACTC1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ACTC1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ACTC1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Signal Transduction

42,019 Da

actin, alpha, cardiac muscle 1

actin, alpha cardiac muscle 1

Actin, alpha cardiac muscle 1

ACTC  [Similar Products]

ACTC_HUMAN

Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). [provided by RefSeq, Jul 2008]

ACTC1: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Belongs to the actin family.

Protein type: Cell development/differentiation; Contractile; Myosin-binding; Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 15q14

Cellular Component: I band; extracellular space; sarcomere; focal adhesion; membrane; cytoplasm; actin filament; cytosol

Molecular Function: myosin binding; ATPase activity; ATP binding

Biological Process: response to drug; actin filament-based movement; apoptosis; metabolic process; muscle thin filament assembly; actomyosin structure organization and biogenesis; cardiac myofibril assembly; muscle filament sliding; response to ethanol; heart contraction; cardiac muscle morphogensis; actin-myosin filament sliding; cardiac muscle contraction; negative regulation of apoptosis

Disease: Atrial Septal Defect 5; Cardiomyopathy, Familial Hypertrophic, 11; Cardiomyopathy, Dilated, 1r

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