ADGRG6, Polyclonal Antibody

APG1; DREG; VIGR; LCCS9; PR126; GPR126; PS1TP2

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

IgG

Rabbit

The antibody detects endogenous levels of total ADGRG6 protein.

Antigen affinity purification

pH 7.4 PBS, 0.05% NaN3, 40% Glycerol

0.3 mg/mL (lot specific)

Store at -20 degree C.

Small volumes of anti-ADGRG6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

This gene, which is upregulated in human umbilical vein endothelial cells, encodes a G protein-coupled receptor. Variations in this gene can affect a person's stature. Multiple transcript variants encoding different proteins have been found for this gene.

Total protein Ab

Immunohistochemistry (IHC)

IHC: 1:25-100

The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 47595(ADGRG6 Antibody) at dilution 1/20.(Original magnification: 200)

The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using 47595(ADGRG6 Antibody) at dilution 1/20.(Original magnification: 200)

133,671 Da

adhesion G protein-coupled receptor G6

adhesion G-protein coupled receptor G6

Adhesion G-protein coupled receptor G6

ADGRG6-NTF; ADGRG6-CTF  [Similar Products]

This gene, which is upregulated in human umbilical vein endothelial cells, encodes a G protein-coupled receptor. Variations in this gene can affect a person's stature. Multiple transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Mar 2009]

G-protein coupled receptor which is activated by type IV collagen, a major constituent of the basement membrane (). Couples to G(i)-proteins as well as G(s)-proteins (PubMed:24227709). Essential for normal differentiation of promyelinating Schwann cells and for normal myelination of axons (PubMed:24227709). Regulates neural, cardiac and ear development via G-protein- and/or N-terminus-dependent signaling (). May act as a receptor for PRNP which may promote myelin homeostasis ().

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