Product Name
ATP Binding Cassette Transporter C8 (ABCC8), Antibody Pair Kit
Full Product Name
ATP Binding Cassette Transporter C8 (ABCC8) Antibody Pair Kit (with Standard)
Product Synonym Names
ABC-C8; PHHI; MRP8; ABC36; HHF1; HI; HRINS; SUR; SUR1; TNDM2; Sulfonylurea Receptor(Hyperinsulinemia)
Product Gene Name
ABCC8 antibody pair kit
[Similar Products]
Matching Pairs
Antibody: ATP Binding Cassette Transporter C8 (ABCC8) (MBS2102625)
Pairing: ATP Binding Cassette Transporter C8 (ABCC8) (MBS2102625)
Comments: Matched antibody pair kit containing antibody/standard combination
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for Q09428
Samples
Tissue Homogenates, Cell Lysates and Other Biological Fluids
Detection Range
2.5-40ng/mL
Standard
Recombinant ABCC8 (Lyophilized, 1 vial-10ug)
Capture Antibody
Rabbit polyclonal antibody (Liquid, 1 vial-400mug/800muL)
Detection Antibody
Biotinylated Rabbit polyclonal antibody (Liquid, 1 vial-100mug/500muL)
Producte Usage
Raw materials can be used for preparation of 5x96T or 10x96T ELISA Kits.
Antibody Support Pack
Antibody Support Pack (Buffer Pack) is sold separately as catalog #MBS2090685
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customerâs specifications, please inquire.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of ABCC8 antibody pair kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for ABCC8 antibody pair kit
Signal transduction;
Applications Tested/Suitable for ABCC8 antibody pair kit
ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex
NCBI/Uniprot data below describe general gene information for ABCC8. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001274103.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001287174.1
[Other Products]
UniProt Primary Accession #
Q09428
[Other Products]
UniProt Secondary Accession #
O75948; Q16583; A6NMX8; E3UYX6[Other Products]
UniProt Related Accession #
Q09428[Other Products]
Molecular Weight
5,468 Da
NCBI Official Full Name
ATP-binding cassette sub-family C member 8 isoform 1
NCBI Official Synonym Full Names
ATP binding cassette subfamily C member 8
NCBI Official Symbol
ABCC8 [Similar Products]
NCBI Official Synonym Symbols
HI; SUR; HHF1; MRP8; PHHI; SUR1; ABC36; HRINS; TNDM2; SUR1delta2
[Similar Products]
NCBI Protein Information
ATP-binding cassette sub-family C member 8
UniProt Protein Name
ATP-binding cassette sub-family C member 8
UniProt Synonym Protein Names
Sulfonylurea receptor 1
Protein Family
ABC transporter C family
UniProt Gene Name
ABCC8 [Similar Products]
UniProt Synonym Gene Names
HRINS; SUR; SUR1 [Similar Products]
NCBI Summary for ABCC8
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]
UniProt Comments for ABCC8
Subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive K+ channels and insulin release.
Research Articles on ABCC8
1. T(p.D897V) of ABCC8 gene.">The patient carries a heterozygous mutation c.2690A>T(p.D897V) of ABCC8 gene.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.