Product Name
ABTB1 (ABTB1 (HGNC:18275)), Blocking Peptide
Full Product Name
ABTB1 Antibody (C-term) Blocking Peptide
Product Synonym Names
Ankyrin repeat and BTB/POZ domain-containing protein 1; Elongation factor 1A-binding protein; ABTB1
Product Gene Name
ABTB1 (HGNC:18275) blocking peptide
[Similar Products]
Antibody/Peptide Pairs
ABTB1 peptide (MBS9222436) is used for blocking the activity of ABTB1 antibody (MBS9201963)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q969K4
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Cellular Location
Cytoplasm.
Tissue Location
Ubiquitously expressed in all fetal tissues examined including heart, brain, liver, and kidney. Also expressed at lower levels in both ***** heart and hypertrophic heart
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Other Notes
Small volumes of ABTB1 (HGNC:18275) blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ABTB1 (HGNC:18275) blocking peptide
May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes.
NCBI/Uniprot data below describe general gene information for ABTB1 (HGNC:18275). It may not necessarily be applicable to this product.
NCBI Accession #
Q969K4.1
[Other Products]
UniProt Primary Accession #
Q969K4
[Other Products]
UniProt Secondary Accession #
Q6ZNU9; Q71MF1; Q96S62; Q96S63; D3DNB0[Other Products]
UniProt Related Accession #
Q969K4[Other Products]
Molecular Weight
44,428 Da
NCBI Official Full Name
Ankyrin repeat and BTB/POZ domain-containing protein 1
NCBI Official Synonym Full Names
ankyrin repeat and BTB domain containing 1
NCBI Official Symbol
ABTB1 [Similar Products]
NCBI Official Synonym Symbols
BPOZ; BTB3; BTBD21; EF1ABP; PP2259
[Similar Products]
NCBI Protein Information
ankyrin repeat and BTB/POZ domain-containing protein 1
UniProt Protein Name
Ankyrin repeat and BTB/POZ domain-containing protein 1
UniProt Synonym Protein Names
Elongation factor 1A-binding protein
UniProt Gene Name
ABTB1 [Similar Products]
UniProt Entry Name
ABTB1_HUMAN
NCBI Summary for ABTB1 (HGNC:18275)
This gene encodes a protein with an ankyrin repeat region and two BTB/POZ domains, which are thought to be involved in protein-protein interactions. Expression of this gene is activated by the phosphatase and tensin homolog, a tumor suppressor. Alternate splicing results in three transcript variants. [provided by RefSeq, Mar 2010]
UniProt Comments for ABTB1 (HGNC:18275)
ABTB1: May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Translation; RNA-binding
Chromosomal Location of Human Ortholog: 3q21
Cellular Component: cytoplasm; nucleolus; plasma membrane
Molecular Function: protein binding
Research Articles on ABTB1 (HGNC:18275)
1. BPOZ-2 promoted eEF1A1 ubiquitylation and degradation, suggesting that eEF1A1 is a substrate of BPOZ-2.
Precautions
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Disclaimer
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