Full Product Name
USB1 Antibody, FITC conjugated
Product Synonym Names
U6 snRNA phosphodiesterase; USB1
Product Gene Name
anti-USB1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9BQ65
Purity/Purification
>95%, Protein G purified
Immunogen
Recombinant Human U6 snRNA phosphodiesterase protein (1-90AA)
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-USB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-USB1 antibody
Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA 3' end-terminated with a 2', 3'-cyclic phosphate.
Product Categories/Family for anti-USB1 antibody
Applications Tested/Suitable for anti-USB1 antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for USB1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001182231.1
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NCBI GenBank Nucleotide #
NM_001195302.1
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UniProt Primary Accession #
Q9BQ65
[Other Products]
UniProt Secondary Accession #
Q96FZ9; Q9H8X8; B4DWE3; B4DZW5[Other Products]
UniProt Related Accession #
Q9BQ65[Other Products]
Molecular Weight
20,802 Da
NCBI Official Full Name
U6 snRNA phosphodiesterase isoform 2
NCBI Official Synonym Full Names
U6 snRNA biogenesis phosphodiesterase 1
NCBI Official Symbol
USB1 [Similar Products]
NCBI Official Synonym Symbols
PN; Mpn1; HVSL1; hUsb1; C16orf57
[Similar Products]
NCBI Protein Information
U6 snRNA phosphodiesterase
UniProt Protein Name
U6 snRNA phosphodiesterase
Protein Family
U6 snRNA phosphodiesterase
UniProt Gene Name
USB1 [Similar Products]
UniProt Synonym Gene Names
hUsb1 [Similar Products]
NCBI Summary for USB1
This gene encodes a protein with several conserved domains, however, its exact function is not known. Mutations in this gene are associated with poikiloderma with neutropenia (PN), which shows phenotypic overlap with Rothmund-Thomson syndrome (RTS) caused by mutations in the RECQL4 gene. It is believed that this gene product interacts with RECQL4 protein via SMAD4 proteins, explaining the partial clinical overlap between PN and RTS. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Mar 2011]
UniProt Comments for USB1
Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate.
Research Articles on USB1
1. Data indicate the enzymatic activities and structures of yeast and human U6 RNA processing enzyme Usb1.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
