Full Product Name
AGXT Polyclonal Antibody
Product Synonym Names
AGT; AGT1; AGXT1; PH1; SPAT; SPT; TLH6
Product Gene Name
anti-AGXT antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
DSVASLGGTP LYMDRQGIDI LYSGSQKALN APPGTSLISF SDKAKKKMYS RKTKPFSFYL DIKWLANFWG CDDQPRMYHH TIPVISLYSL RESLALIAEQ GLENSWRQHR EAAAYLHGRL QALGLQLFVK DPALRLPTVT TVAVPAGYDW RDIVSYVIDH FDIEIMGGLG PSTGKVLRIG LLGCNATREN VDRVTEALRA ALQHCPKKKL
3D Structure
ModBase 3D Structure for P21549
Species Reactivity
Mouse, Rat
Purity/Purification
Affinity Purification
Immunogen
Recombinant protein of human AGXT
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Cellular Location
Mitochondrion, Peroxisome
Positive Samples
Rat skeletal muscle
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Other Notes
Small volumes of anti-AGXT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-AGXT antibody
This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria.
Product Categories/Family for anti-AGXT antibody
Polyclonal Antibodies
Applications Tested/Suitable for anti-AGXT antibody
Western Blot (WB)
Application Notes for anti-AGXT antibody
WB: 1:500 - 1:2000
Western Blot (WB) of anti-AGXT antibody
Western blot analysis of extracts of rat skeletal muscle, using AGXT antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit.
Exposure time: 10s.
NCBI/Uniprot data below describe general gene information for AGXT. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000021.1
[Other Products]
NCBI GenBank Nucleotide #
NM_000030.2
[Other Products]
UniProt Primary Accession #
P21549
[Other Products]
UniProt Secondary Accession #
Q53QU6[Other Products]
UniProt Related Accession #
P21549[Other Products]
Molecular Weight
Calculated: 43kDa
Observed: 43kDa
NCBI Official Full Name
serine--pyruvate aminotransferase
NCBI Official Synonym Full Names
alanine-glyoxylate aminotransferase
NCBI Official Symbol
AGXT [Similar Products]
NCBI Official Synonym Symbols
AGT; PH1; SPT; AGT1; SPAT; TLH6; AGXT1
[Similar Products]
NCBI Protein Information
serine--pyruvate aminotransferase
UniProt Protein Name
Serine--pyruvate aminotransferase
UniProt Synonym Protein Names
Alanine--glyoxylate aminotransferase (EC:2.6.1.44); AGT
Protein Family
Serine--pyruvate aminotransferase
UniProt Gene Name
AGXT [Similar Products]
UniProt Synonym Gene Names
AGT1; SPAT; SPT; AGT [Similar Products]
NCBI Summary for AGXT
This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. [provided by RefSeq, Jul 2008]
Research Articles on AGXT
1. this study identifies a novel AGXT gene mutation in primary hyperoxaluria after kidney transplantation failure in Tunisian patient
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
