Full Product Name
AGXT Antibody
Product Synonym Names
Serine--pyruvate aminotransferase; SPT; Alanine--glyoxylate aminotransferase (EC:2.6.1.44); AGT; AGXT; AGT1; SPAT
Product Gene Name
anti-AGXT antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P21549
Purity/Purification
>95%, Protein G purified
Immunogen
Recombinant Human Serine--pyruvate aminotransferase protein (112-294AA)
Conjugation
Non-conjugated
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-AGXT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-AGXT antibody
intracellular membrane-bounded organelle, peroxisomal matrix, peroxisome, alanine-glyoxylate transaminase activity, amino acid binding, protein homodimerization activity, protein self-association, pyridoxal phosphate binding, receptor binding, serine-pyruvate transaminase activity
Product Categories/Family for anti-AGXT antibody
Metabolism; Signal transduction
Applications Tested/Suitable for anti-AGXT antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-AGXT antibody
WB: 1:500-1:5000
IHC: 1:20-1:200
Western Blot (WB) of anti-AGXT antibody
Western Blot
Positive WB detected in: A549 whole cell lysate, MCF-7 whole cell lysate
All lanes: Agxt antibody at 3ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 46, 44 KDa
Observed band size: 46 KDa
Immunohistochemistry (IHC) of anti-AGXT antibody
Immunohistochemistry of paraffin-embedded human liver tissue using MBS7104749 at dilution of 1:100
Immunohistochemistry (IHC) of anti-AGXT antibody
Immunohistochemistry of paraffin-embedded human liver cancer using MBS7104749 at dilution of 1:100
NCBI/Uniprot data below describe general gene information for AGXT. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000021.1
[Other Products]
NCBI GenBank Nucleotide #
NM_000030.2
[Other Products]
UniProt Primary Accession #
P21549
[Other Products]
UniProt Secondary Accession #
Q53QU6[Other Products]
UniProt Related Accession #
P21549[Other Products]
Molecular Weight
43,010 Da
NCBI Official Full Name
serine--pyruvate aminotransferase
NCBI Official Synonym Full Names
alanine-glyoxylate aminotransferase
NCBI Official Symbol
AGXT [Similar Products]
NCBI Official Synonym Symbols
AGT; PH1; SPT; AGT1; SPAT; TLH6; AGXT1
[Similar Products]
NCBI Protein Information
serine--pyruvate aminotransferase
UniProt Protein Name
Serine--pyruvate aminotransferase
UniProt Synonym Protein Names
Alanine--glyoxylate aminotransferase (EC:2.6.1.44); AGT
Protein Family
Serine--pyruvate aminotransferase
UniProt Gene Name
AGXT [Similar Products]
UniProt Synonym Gene Names
AGT1; SPAT; SPT; AGT [Similar Products]
NCBI Summary for AGXT
This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. [provided by RefSeq, Jul 2008]
Research Articles on AGXT
1. this study identifies a novel AGXT gene mutation in primary hyperoxaluria after kidney transplantation failure in Tunisian patient
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
