Hepatitis A virus cellular receptor 2 homolog, HAVcr-2, ELISA Kit

Mus musculus; Mouse; Hepatitis A virus cellular receptor 2 homolog; HAVcr-2; T-cell immunoglobulin and mucin domain-containing protein 3; TIMD-3; T-cell membrane protein 3; TIM-3; Havcr2; Tim3; Timd3; TIM-3; Havcr2

For Research Use Only. Not for use in diagnostic procedures.

Store at 4 degree C

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Small volumes of HAVcr-2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9427104 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Hepatitis A virus cellular receptor 2 homolog, HAVcr-2, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing HAVcr-2. The ELISA analytical biochemical technique of the MBS9427104 kit is based on HAVcr-2 antibody-HAVcr-2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HAVcr-2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HAVcr-2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

22,087 Da

hepatitis A virus cellular receptor 2

hepatitis A virus cellular receptor 2 homolog

Hepatitis A virus cellular receptor 2 homolog

Tim3; Timd3; HAVcr-2; TIMD-3; TIM-3  [Similar Products]

TIM-3: Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Receptor for LGALS9. Belongs to the immunoglobulin superfamily. TIM family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 11|11 B1.1

Cellular Component: cell surface; early endosome; immunological synapse

Molecular Function: protein binding

Biological Process: defense response to Gram-positive bacterium; inhibition of NF-kappaB transcription factor; macrophage activation during immune response; maternal process involved in pregnancy; natural killer cell tolerance induction; negative regulation of immune response to tumor cell; negative regulation of innate immune response; negative regulation of interferon type I production; negative regulation of interferon-alpha production; negative regulation of interferon-gamma production; negative regulation of interleukin-2 production; negative regulation of interleukin-3 production; negative regulation of interleukin-6 production; negative regulation of myeloid dendritic cell activation; negative regulation of natural killer cell activation; negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; negative regulation of T cell proliferation; negative regulation of T-helper 1 type immune response; negative regulation of tumor necrosis factor production; positive regulation of chemokine production; positive regulation of cytokine production; positive regulation of innate immune response; positive regulation of interferon-gamma production; positive regulation of interleukin-1 production; positive regulation of interleukin-4 production; positive regulation of macrophage activation; positive regulation of T cell proliferation; regulation of tolerance induction dependent upon immune response; toll-like receptor 3 signaling pathway; toll-like receptor 7 signaling pathway; toll-like receptor 9 signaling pathway

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