Product Synonym Names
ARHGAP2; CHN; DURS2; NC; RHOGAP2
Product Gene Name
anti-CHN1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P15882
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity purification
Immunogen
Recombinant protein of human CHN1
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Aliquot and store at-20 degree C. Avoid repeated freeze/thaw cycles.
Other Notes
Small volumes of anti-CHN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CHN1 antibody
This gene encodes GTPase-activating protein for ras-related p21-rac and a phorbol ester receptor. It is predominantly expressed in neurons, and plays an important role in neuronal signal-transduction mechanisms. Mutations in this gene are associated with Duane' s retraction syndrome 2 (DURS2). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Applications Tested/Suitable for anti-CHN1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-CHN1 antibody
WB: 1:500-1:2000
IHC: 1:50-1:200
NCBI/Uniprot data below describe general gene information for CHN1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001020372.2
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NCBI GenBank Nucleotide #
NM_001025201.3
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UniProt Primary Accession #
P15882
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UniProt Secondary Accession #
Q53SD6; Q53SH5; Q96FB0; A8K1M6; B3KNU6; B4DV19[Other Products]
UniProt Related Accession #
P15882[Other Products]
NCBI Official Full Name
N-chimaerin isoform 2
NCBI Official Synonym Full Names
chimerin 1
NCBI Official Symbol
CHN1 [Similar Products]
NCBI Official Synonym Symbols
NC; CHN; DURS2; ARHGAP2; RHOGAP2
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NCBI Protein Information
N-chimaerin
UniProt Protein Name
N-chimaerin
UniProt Synonym Protein Names
A-chimaerin; Alpha-chimerin; N-chimerin; NC; Rho GTPase-activating protein 2
Protein Family
N-chimaerin
UniProt Gene Name
CHN1 [Similar Products]
UniProt Synonym Gene Names
ARHGAP2; CHN; NC [Similar Products]
NCBI Summary for CHN1
This gene encodes GTPase-activating protein for ras-related p21-rac and a phorbol ester receptor. It is predominantly expressed in neurons, and plays an important role in neuronal signal-transduction mechanisms. Mutations in this gene are associated with Duane's retraction syndrome 2 (DURS2). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]
UniProt Comments for CHN1
GTPase-activating protein for p21-rac and a phorbol ester receptor. Involved in the assembly of neuronal locomotor circuits as a direct effector of EPHA4 in axon guidance.
Research Articles on CHN1
1. CHN1 and TNFAIP3 are candidate biomarkers for esophageal squamous cell carcinomas
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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