Product Name
N-chimaerin (Chn1), Recombinant Protein
Full Product Name
Recombinant Rat N-chimaerin (Chn1)
Product Gene Name
Chn1 recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-334aa, Full length protein
Sequence
MPSKESWSGR KTNRATVHKS KQEGRQQDLL IAALGMKLGS QKSSVTIWQP LKLFAYSQLT SLVRRATLKE NEQIPKYEKV HNFKVHTFRG PHWCEYCANF MWGLIAQGVK CADCGLNVHK QCSKMVPNDC KPDLKHVKKV YSCDLTTLVK AHITKRPMVV DMCIREIESR GLNSEGLYRV SGFSDLIEDV KMAFDRDGEK ADISVNMYED INIITGALKL YFRDLPIPLI TYDAYPKFIE SAKIVDPDEQ LETLHEALRS LPPAHCETLR YLMAHLKRVT LHEKENLMSA ENLGIVFGPT LMRSPELDPM AALNDIRYQR LVVELLIKNE DILF
3D Structure
ModBase 3D Structure for P30337
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Chn1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Chn1 recombinant protein
This gene encodes GTPase-activating protein for p21-rac and a phorbol ester receptor. It plays an important role in ocular motor axon pathfinding. Heterozygous missense mutations in this gene cause Duane s retraction syndrome 2 (DURS2). Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI/Uniprot data below describe general gene information for Chn1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_114472.1
[Other Products]
NCBI GenBank Nucleotide #
NM_032083.1
[Other Products]
UniProt Primary Accession #
P30337
[Other Products]
UniProt Secondary Accession #
Q505J4[Other Products]
UniProt Related Accession #
P30337[Other Products]
Molecular Weight
38,224 Da
NCBI Official Full Name
N-chimaerin
NCBI Official Synonym Full Names
chimerin 1
NCBI Official Symbol
Chn1 [Similar Products]
NCBI Protein Information
N-chimaerin
UniProt Protein Name
N-chimaerin
UniProt Synonym Protein Names
A-chimaerin; Alpha-chimerin; N-chimerin; NC; Rho GTPase-activating protein 2
Protein Family
N-chimaerin
UniProt Gene Name
Chn1 [Similar Products]
UniProt Synonym Gene Names
Arhgap2; Chn; NC [Similar Products]
NCBI Summary for Chn1
expressed only in neurons; may mediate neuronal signal transductions; human homolog functions as GTPase-activating protein (GAP) for p21rac and phorbol ester receptor [RGD, Feb 2006]
UniProt Comments for Chn1
GTPase-activating protein for p21-rac and a phorbol ester receptor. Involved in the assembly of neuronal locomotor circuits as a direct effector of EPHA4 in axon guidance.
Research Articles on Chn1
1. serum levels decreased significantly as gestation progressed
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
