Full Product Name
ACTC1 Antibody (Rabbit Polyclonal)
Product Gene Name
anti-ACTC1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human
Predicted: Rat, Mouse
Form/Format
Purified by protein affinity column containing 1% BSA and 0.02% NaN3
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
Other Notes
Small volumes of anti-ACTC1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ACTC1 antibody
Rabbit polyclonal ACTC1 (1) antibody was raised against a recombinate human ACTC1 protein 44a-269aa (BC009978).
Applications Tested/Suitable for anti-ACTC1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ACTC1 antibody
ELISA: 1:20,000-1:80,000
WB: 1:200-1:1,000
IHC: 1:100-1:500
NCBI/Uniprot data below describe general gene information for ACTC1. It may not necessarily be applicable to this product.
NCBI Accession #
BC009978
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UniProt Secondary Accession #
P04270[Other Products]
UniProt Related Accession #
P68032[Other Products]
Molecular Weight
42,019 Da
NCBI Official Full Name
Homo sapiens actin, alpha, cardiac muscle 1, mRNA
NCBI Official Synonym Full Names
actin, alpha, cardiac muscle 1
NCBI Official Symbol
ACTC1 [Similar Products]
NCBI Official Synonym Symbols
ACTC; ASD5; CMD1R; CMH11; LVNC4
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NCBI Protein Information
actin, alpha cardiac muscle 1
UniProt Protein Name
Actin, alpha cardiac muscle 1
UniProt Synonym Protein Names
Alpha-cardiac actin
UniProt Gene Name
ACTC1 [Similar Products]
UniProt Synonym Gene Names
ACTC [Similar Products]
NCBI Summary for ACTC1
Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). [provided by RefSeq, Jul 2008]
UniProt Comments for ACTC1
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
Research Articles on ACTC1
1. These findings suggest that the familial ostium secundum atrial septal defect (ASDII)may be a result of an ACTC1 3'UTR gain-of-function mutation caused by the introduction of a new miR-139-5p target site. Our results provide the first evidence of a pathogenic mutation in the ACTC1 3'UTR that may be associated with familial isolated ASDII.
Precautions
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Disclaimer
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