Full Product Name
CFHR1 Antibody, Biotin Conjugated
Product Synonym Names
Complement factor H-related protein 1; FHR-1; H factor-like protein 1; H-factor-like 1; H36; CFHR1; CFHL; CFHL1; CFHL1P; CFHR1P; FHR1; HFL1; HFL2
Product Gene Name
anti-CFHR1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q03591
Purity/Purification
>95%
Protein G Purified
Immunogen
Recombinant Human Complement factor H-related protein 1 protein (132-221AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at-20 degree C or-80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-CFHR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-CFHR1 antibody
Cardiovascular
Applications Tested/Suitable for anti-CFHR1 antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for CFHR1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_002104.2
[Other Products]
NCBI GenBank Nucleotide #
NM_002113.2
[Other Products]
UniProt Primary Accession #
Q03591
[Other Products]
UniProt Secondary Accession #
Q3B774; Q9UJ17; A8K465[Other Products]
UniProt Related Accession #
Q03591[Other Products]
Molecular Weight
37,651 Da
NCBI Official Full Name
complement factor H-related protein 1
NCBI Official Synonym Full Names
complement factor H related 1
NCBI Official Symbol
CFHR1 [Similar Products]
NCBI Official Synonym Symbols
CFHL; FHR1; HFL1; HFL2; CFHL1; H36-1; H36-2; CFHL1P; CFHR1P
[Similar Products]
NCBI Protein Information
complement factor H-related protein 1
UniProt Protein Name
Complement factor H-related protein 1
UniProt Synonym Protein Names
H factor-like protein 1; H-factor-like 1; H36
Protein Family
Complement factor H-related protein
UniProt Gene Name
CFHR1 [Similar Products]
UniProt Synonym Gene Names
CFHL; CFHL1; CFHL1P; CFHR1P; FHR1; HFL1; HFL2; FHR-1; H-factor-like 1 [Similar Products]
NCBI Summary for CFHR1
This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome. [provided by RefSeq, Oct 2009]
UniProt Comments for CFHR1
Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism.
Research Articles on CFHR1
1. Novel genetic rearrangement generated from a heterozygous deletion spanning 146 Kbp involving multiple CFHR genes leading to a CFHR1-R5 hybrid protein. This deletion was found in four family members presenting with a familial dominant glomerulopathy.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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