Product Name
Follicle Stimulating Hormone (FSH), Protein
Popular Item
Full Product Name
Follicle Stimulating Hormone (FSH), Human Pituitary - High Purity
Product Synonym Names
Follicle Stimulating Hormone (FSH), Native Human Hormone - >=95% (SDS-PAGE), FSH
Product Gene Name
FSH protein
[Similar Products]
Matching Pairs
Antibody: Follicle Stimulating Hormone (FSH) (MBS170676)
Antigen: Follicle Stimulating Hormone (MBS173364)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Host
Human Pituitary Glands
Purity/Purification
?95% as determined by SDS-PAGE
Immunogen affinity purified
Appearance
White, lyophilized powder.
Handling
Handle as a potentially hazardous substance.
Reconstitution
Neutral pH buffer of choice. Avoid extreme high and low pH.
Contaminants
All contaminants are < or = 0.5% w/w
hGh: <0.001mg/mg
LH: <10IU/mg
PRL: <0.001mg/mg
TSH: <0.01 IU/mg
Activity
4400 IU/mg (WHO 2nd IRP hMG)
Preparation and Storage
Store at 2-8°C
Note: Protect from moisture.
Aliquot and freeze at -20°C after reconstitution.
Shipping: Cold pack
Other Notes
Small volumes of FSH protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
FSH protein
MyBioSource produces Human Follicle Stimulating Hormone (FSH) for research and clinical diagnostic manufacuting assays.
Technical support, bulk quantities and aliquoting available.
FSH is a hormone found in humans and other animals and is synthesized and secreted by gonadotrophs of the anterior pituitary gland. FSH regulates the development, growth, pubertal maturation, and reproductive processes of the body. FSH and Luteinizing hormone (LH) act synergistically in reproduction.
Product Categories/Family for FSH protein
Proteins; Antigens; Standards/controls; Native Proteins; Follicle Stimulating Hormone (fsh)
NCBI/Uniprot data below describe general gene information for FSH. It may not necessarily be applicable to this product.
NCBI Accession #
AAA52476.1
[Other Products]
UniProt Secondary Accession #
Q14D61; A2TF08; A5JVV3[Other Products]
UniProt Related Accession #
P01225[Other Products]
NCBI Official Full Name
follicle-stimulating hormone
NCBI Official Synonym Full Names
follicle stimulating hormone, beta polypeptide
NCBI Official Symbol
FSHB [Similar Products]
NCBI Protein Information
follitropin subunit beta; FSH-B; FSH-beta; follitropin beta chain; follitropin, beta chain; follicle-stimulating hormone beta subunit
UniProt Protein Name
Follitropin subunit beta
UniProt Synonym Protein Names
Follicle-stimulating hormone beta subunit; FSH-B; FSH-beta; Follitropin beta chain
UniProt Gene Name
FSHB [Similar Products]
UniProt Synonym Gene Names
FSH-B; FSH-beta [Similar Products]
UniProt Entry Name
FSHB_HUMAN
NCBI Summary for FSH
The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. All of these glycoproteins consist of an identical alpha subunit and a hormone-specific beta subunit. This gene encodes the beta subunit of follicle-stimulating hormone. In conjunction with luteinizing hormone, follicle-stimulating hormone induces egg and sperm production. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
UniProt Comments for FSH
FSHB: Stimulates development of follicle and spermatogenesis in the reproductive organs. Defects in FSHB are a cause of isolated follicle- stimulating hormone deficiency (IFSHD). Selective follicle-stimulating hormone deficiency is an uncommon cause of infertility, producing amenorrhea and hypogonadism in women and oligo or azoospermia with normal testosterone levels in normally virilised men. Belongs to the glycoprotein hormones subunit beta family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 11p13
Cellular Component: cytoplasm; extracellular region
Molecular Function: follicle-stimulating hormone activity; protein binding; hormone activity
Biological Process: progesterone biosynthetic process; follicle-stimulating hormone signaling pathway; peptide hormone processing; female gamete generation; Sertoli cell proliferation; female pregnancy; signal transduction; cellular protein metabolic process; regulation of osteoclast differentiation; transforming growth factor beta receptor signaling pathway; positive regulation of cell proliferation; positive regulation of bone resorption; positive regulation of transcription from RNA polymerase II promoter; positive regulation of cell migration
Disease: Follicle-stimulating Hormone Deficiency, Isolated
Research Articles on FSH
1. The combined effect of FSHB GG+FSHR AA may potentiate the FSH pathway, which increases serum levels of FSH and reduces antimullerian hormone in health girls.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
