Full Product Name
GHRHR Antibody
Product Synonym Names
GHRFR; GHRH receptor; GHRHRpsv; GRF receptor; GRFR; growth hormone-releasing hormone receptor
Product Gene Name
anti-GHRHR antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q02643
Species Reactivity
Human, Mouse, Rat
Specificity
GHRHR antibody detects endogenous levels of total GHRHR protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human GHRHR.
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-GHRHR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-GHRHR antibody
Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
Applications Tested/Suitable for anti-GHRHR antibody
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-GHRHR antibody
WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:1000
Testing Data of anti-GHRHR antibody
Western Blot (WB) of anti-GHRHR antibody
Peptide-+ Western blot analysis of extracts from LOVO cells, using GHRHR antibody. Immunofluorescence analysis of HUVEC cells, using GHRHR antibody.
NCBI/Uniprot data below describe general gene information for GHRHR. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000814.2
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NCBI GenBank Nucleotide #
NM_000823.3
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UniProt Primary Accession #
Q02643
[Other Products]
UniProt Secondary Accession #
Q99863[Other Products]
UniProt Related Accession #
Q02643[Other Products]
Molecular Weight
47,402 Da
NCBI Official Full Name
growth hormone-releasing hormone receptor
NCBI Official Synonym Full Names
growth hormone releasing hormone receptor
NCBI Official Symbol
GHRHR [Similar Products]
NCBI Official Synonym Symbols
GRFR; GHRFR; IGHD1B
[Similar Products]
NCBI Protein Information
growth hormone-releasing hormone receptor
UniProt Protein Name
Growth hormone-releasing hormone receptor
UniProt Synonym Protein Names
Growth hormone-releasing factor receptor; GRF receptor; GRFR
Protein Family
Growth hormone-releasing hormone receptor
UniProt Gene Name
GHRHR [Similar Products]
UniProt Synonym Gene Names
GHRH receptor; GRF receptor; GRFR [Similar Products]
NCBI Summary for GHRHR
This gene encodes a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. Mutations in this gene have been associated with isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, a disorder characterized by short stature. [provided by RefSeq, Jun 2010]
UniProt Comments for GHRHR
Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion.
Product References and Citations for anti-GHRHR antibody
Mayo K.E.; Mol. Endocrinol. 6:1734-1744(1992). Gaylinn B.D., Mol. Endocrinol. 7:77-84(1993). Hillier L.W., Nature 424:157-164(2003).
Research Articles on GHRHR
1. GHRHR mutation is associated with growth hormone deficiency.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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